ADRA2B

Gene Symbol ADRA2B
Entrez Gene 151
Alt Symbol ADRA2L1, ADRA2RL1, ADRARL1, ALPHA2BAR, alpha-2BAR
Species Human
Gene Type protein-coding
Description adrenoceptor alpha 2B
Other Description ADRA2B adrenergic, alpha-2B-, receptor|G-protein coupled receptor|alpha-2 adrenergic receptor subtype C2|alpha-2-adrenergic receptor-like 1|alpha-2B adrenergic receptor|alpha-2B adrenoreceptor
Swissprots Q9BZK0 Q4TUH9 P18089 Q53RF2
Accessions AAA51666 AAA62823 AAB62558 AAK01635 AAS55646 AAX93218 AAY43127 ABY87536 EAW71390 P18089 AA887330 BC133021 AAI33022 BC136537 AAI36538 BF475329 CV806541 NM_000682 NP_000673
Function Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol. {ECO:0000269|PubMed:23105096}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:23105096}; Multi-pass membrane protein {ECO:0000269|PubMed:23105096}. Note=Interaction with RAB26 mediates transport from the Golgi to the cell membrane.
Top Pathways cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction

α 2B -AR (C-4) - sc-390429 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
α<sub>2B</sub>-AR (C-4): sc-390429. Western blot analysis of α<sub>2B</sub>-AR expression in Hep G2 whole cell lysate.

α 2B -AR (G-9) - sc-390430 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
α<sub>2B</sub>-AR (G-9): sc-390430. Western blot analysis of α<sub>2B</sub>-AR expression in Hep G2 whole cell lysate.

α 2B -AR (H-96) - sc-10723 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
α<sub>2B</sub>-AR (H-96): sc-10723. Immunofluorescence staining of normal mouse intestine frozen section showing membrane staining.

α 2B -AR (E-20) - sc-31353 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

α 2B -AR (P-19) - sc-31354 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

α 2B -AR (C-19) - sc-1479 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-alpha 2b Adrenergic Receptor antibody - ab91468 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-alpha 2b Adrenergic Receptor antibody (ab91468) at 1/100 dilution + MDA-MB231 cell line lysate at 35 µg

Anti-alpha 2b Adrenergic Receptor antibody - ab196676 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of HepG2 cells labeling alpha 2b Adrenergic Receptor with ab196676 at 1/100 dilution, in the presence (right panel) or absence (left panel) of immunizing peptide.

Anti-alpha 2b Adrenergic Receptor antibody - ab49689 from Abcam

Host Chicken
Clonality Polyclonal
Anti-alpha 2b Adrenergic Receptor antibody (ab49689) at 1/2000 dilution + E coli-derived fusion protein at 15 µgSecondaryGoat anti-IgY-HRP at 1000

Anti-alpha 2b Adrenergic Receptor antibody [EPR9623] - ab151727 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9623
All lanes : Anti-alpha 2b Adrenergic Receptor antibody [EPR9623] (ab151727) at 1/10000 dilutionLane 1 : Human fetal brain lysateLane 2 : MCF7 cell lysateLane 3 : HepG2 cell lysate Lane 4 : 293T cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-ADRA2B Antibody (Internal, AP) - LS-C274943 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ADRA2B Antibody (Internal, APC) - LS-C274944 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ADRA2B Antibody (Internal, Biotin) - LS-C274945 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ADRA2B Antibody (aa161-210) - LS-C118805 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of HepG2 cells, using Adrenergic Receptor alpha-2B Antibody. The picture on the right is treated with the synthesized peptide.

Anti-ADRA2B Antibody (Internal, FITC) - LS-C274946 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ADRA2B Antibody (Internal, Azide-free, HRP) - LS-C274947 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ADRA2B Antibody (Internal, PE) - LS-C274948 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ADRA2B Antibody (Internal) - LS-C330327 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ADRA2B Antibody - LS-C26798 from LifeSpan Bioscience

Prices $460.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot of alpha2B adrenergic receptor antibody on MDCK cells transfected to produce alpha2B receptor protein.

Anti-ADRA2B Antibody (aa343-369) - LS-C156114 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human breast carcinoma with ADRA2B Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

alpha-2B Adrenergic R/ADRA2B Antibody - NBP1-55578 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: alpha 2b Adrenergic Receptor Antibody [NBP1-55578] - Analysis of HepG2 cells, using alpha 2b Adrenergic Receptor Antibody. The picture on the right is treated with the synthesized peptide.

ANTI-ADRA2B (CENTER) antibody produced in rabbit - SAB1307233 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ADRA2B (Center): <B>Cat. No. SAB1307233</B>: Western blot analysis of ADRA2B Antibody (Center) in MDA-MB231 cell line lysates (35 μg/lane).

Anti-α-2B Adrenergic Receptor antibody produced in chicken - GW21007A from Sigma-Aldrich

Prices $267.50
Sizes 50 µg
Host Chicken
Clonality Polyclonal

Anti-Adrenergic Receptor α-2B antibody produced in rabbit - SAB4500555 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-Adrenergic Receptor α-2B: <B>Cat. No. SAB4500555</B>: Immunofluorescence of HepG2 cells using Anti-Adrenergic Receptor α-2B antibody. Cells on the left were treated with the Anti-Adrenergic Receptor α-2B antibody. Cells on the right (negative control) were treated with both Anti-Adrenergic Receptor α-2B antibody and the synthesized immunogen peptide.

ADRA2B-Antibody-Center - AP8566c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of ADRA2B Antibody (Center) (Cat. #AP8566c) in MDA-MB231 cell line lysates (35ug/lane). ADRA2B (arrow) was detected using the purified Pab.
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