ADRA2B

Gene Symbol ADRA2B
Entrez Gene 151
Alt Symbol ADRA2L1, ADRA2RL1, ADRARL1, ALPHA2BAR, alpha-2BAR
Species Human
Gene Type protein-coding
Description adrenoceptor alpha 2B
Other Description ADRA2B adrenergic, alpha-2B-, receptor|G-protein coupled receptor|alpha-2 adrenergic receptor subtype C2|alpha-2-adrenergic receptor-like 1|alpha-2B adrenergic receptor|alpha-2B adrenoreceptor
Swissprots Q9BZK0 Q4TUH9 P18089 Q53RF2
Accessions AAA51666 AAA62823 AAB62558 AAK01635 AAS55646 AAX93218 AAY43127 ABY87536 EAW71390 P18089 AA887330 BC133021 AAI33022 BC136537 AAI36538 BF475329 CV806541 NM_000682 NP_000673
Function Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol. {ECO:0000269|PubMed:23105096}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:23105096}; Multi-pass membrane protein {ECO:0000269|PubMed:23105096}. Note=Interaction with RAB26 mediates transport from the Golgi to the cell membrane.
Top Pathways cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction

ADRA2B Antibody Blocking Peptide - LS-E9645 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ADRA2B-Antibody-Center-Blocking-Peptide - BP8566c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

ADRA2B fusion protein - ag19787 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human ADRA2B, His-tagged - ADRA2B-3332H from Creative Biomart

Category Protein
Source E. Coli or Yeast
Species Human

Alpha-2B adrenergic receptor (ADRA2B) - MBS955671 from MyBioSource

Category Protein
Prices $1,375.00, $1,835.00
Sizes 1 mg (E Coli Derived), 1 mg (Yeast Derived)
Source E Coli or Yeast
Species Human

Alpha-2B adrenergic receptor (ADRA2B) - MBS1183271 from MyBioSource

Category Protein
Prices $1,810.00, $2,265.00
Sizes 1 mg (E Coli Derived), 1 mg (Yeast Derived)
Source E Coli or Yeast

Alpha-2B adrenergic receptor (ADRA2B) - MBS1076008 from MyBioSource

Category Protein
Prices $1,810.00, $2,270.00
Sizes 1 mg (E Coli Derived), 1 mg (Yeast Derived)
Source E Coli or Yeast

Alpha-2B adrenergic receptor (ADRA2B) - MBS1050689 from MyBioSource

Category Protein
Prices $1,810.00, $2,270.00
Sizes 1 mg (E Coli Derived), 1 mg (Yeast Derived)
Source E Coli or Yeast

Alpha-2B adrenergic receptor (ADRA2B) - MBS1146178 from MyBioSource

Category Protein
Prices $1,805.00, $2,260.00
Sizes 1 mg (E Coli Derived), 1 mg (Yeast Derived)
Source E Coli or Yeast

Alpha-2B adrenergic receptor (ADRA2B) - MBS1237058 from MyBioSource

Category Protein
Prices $1,805.00, $2,265.00
Sizes 1 mg (E Coli Derived), 1 mg (Yeast Derived)
Source E Coli or Yeast

Alpha-2B adrenergic receptor (ADRA2B) - MBS1138813 from MyBioSource

Category Protein
Prices $1,790.00, $2,250.00
Sizes 1 mg (E Coli Derived), 1 mg (Yeast Derived)
Source E Coli or Yeast

Alpha-2B adrenergic receptor (ADRA2B) - MBS1108634 from MyBioSource

Category Protein
Prices $1,800.00, $2,260.00
Sizes 1 mg (E Coli Derived), 1 mg (Yeast Derived)
Source E Coli or Yeast

ChemiSCREEN™ Human α 2B Adrenergic Receptor Membrane Preparation - HTS157M from EMD Millipore

Prices $596.00
Sizes 200 units
Species Human

alpha-2B Adrenergic R/ADRA2B Recombinant Protein Antigen - NBP2-49470PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E. coli
Species Human

ADRA2B Peptide, Human - M34GP00331H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human
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