ADRA2B

Gene Symbol ADRA2B
Entrez Gene 151
Alt Symbol ADRA2L1, ADRA2RL1, ADRARL1, ALPHA2BAR, alpha-2BAR
Species Human
Gene Type protein-coding
Description adrenoceptor alpha 2B
Other Description ADRA2B adrenergic, alpha-2B-, receptor|G-protein coupled receptor|alpha-2 adrenergic receptor subtype C2|alpha-2-adrenergic receptor-like 1|alpha-2B adrenergic receptor|alpha-2B adrenoreceptor
Swissprots Q9BZK0 Q4TUH9 P18089 Q53RF2
Accessions AAA51666 AAA62823 AAB62558 AAK01635 AAS55646 AAX93218 AAY43127 ABY87536 EAW71390 P18089 AA887330 BC133021 AAI33022 BC136537 AAI36538 BF475329 CV806541 NM_000682 NP_000673
Function Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol. {ECO:0000269|PubMed:23105096}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:23105096}; Multi-pass membrane protein {ECO:0000269|PubMed:23105096}. Note=Interaction with RAB26 mediates transport from the Golgi to the cell membrane.
Top Pathways cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction

α 2B -AR CRISPR/Cas9 KO Plasmid (h) - sc-403430 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

α 2B -AR HDR Plasmid (h) - sc-403430-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

α 2B -AR Double Nickase Plasmid (h) - sc-403430-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

α 2B -AR Double Nickase Plasmid (h2) - sc-403430-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

α 2B -AR CRISPR Activation Plasmid (h) - sc-403430-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

α 2B -AR CRISPR Activation Plasmid (h2) - sc-403430-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

α 2B -AR Lentiviral Activation Particles (h) - sc-403430-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

α 2B -AR Lentiviral Activation Particles (h2) - sc-403430-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

α 2B -AR siRNA (h) - sc-39864 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

α 2B -AR shRNA Plasmid (h) - sc-39864-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

α 2B -AR shRNA (h) Lentiviral Particles - sc-39864-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

alpha-2B Adrenergic R/ADRA2B RNAi - H00000151-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU219671 from Sigma-Aldrich

Category siRNA
Prices $140.00, $140.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2901 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2901 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ADRA2B siRNA (Human) - CRH0105 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ADRA2B - MBS8206936 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Adra2b (NM_000682.5) - SHH232718 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ADRA2B(NM_000682.5) - SHG043903 from Creative biogene

Category siRNA
Species Reactivities Human

Human ADRA2B siRNA - orb260607 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ADRA2B shRNA Plasmid (Human) - CHH0105 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ADRA2B miRNA 3'UTR clone - MiUTR1H-00217 from Creative biogene

Species Reactivities Human
Search more