Gene Symbol | Cd163 |
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Entrez Gene | 93671 |
Alt Symbol | CD163v2, CD163v3 |
Species | Mouse |
Gene Type | protein-coding |
Description | CD163 antigen |
Other Description | scavenger receptor cysteine-rich type 1 protein M130 |
Swissprots | Q99MX8 A6H691 Q2VLH6 Q2VLH5 |
Accessions | EDK99729 Q2VLH6 AF274883 AAK16065 AK032012 BC144848 AAI44849 BC145793 AAI45794 DQ058616 AAY99763 DQ058617 AAY99764 XM_006506800 XP_006506863 NM_001170395 NP_001163866 NM_053094 NP_444324 |
Function | Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium- dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1 (By similarity). {ECO:0000250}. |
Subcellular Location | Soluble CD163: Secreted {ECO:0000250}. |
Tissue Specificity | Expressed in monocytes and mature macrophages such as Kupffer cells in the liver, red pulp macrophages in the spleen and mesenteric lymph nodes. {ECO:0000269|PubMed:11345593}. |
CD163 (M-96) - sc-33560 from Santa Cruz Biotechnology
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CD163 antibody - 10R-6496 from Fitzgerald
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CD163 antibody (biotin) - 61R-1569 from Fitzgerald
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Anti -CD163 (CD163 Molecule, Hemoglobin Scavenger Receptor, M130, MM130, ScavengerReceptor Cysteine-rich Type 1 Protein M130) - 139738 from USBiological Life Science
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Anti -CD163 (CD163 Molecule, Hemoglobin Scavenger Receptor, M130, MM130, ScavengerReceptor Cysteine-rich Type 1 Protein M130) (AP) - 139738-AP from USBiological Life Science
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Anti -CD163 (CD163 Molecule, Hemoglobin Scavenger Receptor, M130, MM130, ScavengerReceptor Cysteine-rich Type 1 Protein M130) (APC) - 139738-APC from USBiological Life Science
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Anti -CD163 (CD163 Molecule, Hemoglobin Scavenger Receptor, M130, MM130, ScavengerReceptor Cysteine-rich Type 1 Protein M130) (Biotin) - 139738-Biotin from USBiological Life Science
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Anti -CD163 (CD163 Molecule, Hemoglobin Scavenger Receptor, M130, MM130, ScavengerReceptor Cysteine-rich Type 1 Protein M130) (FITC) - 139738-FITC from USBiological Life Science
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Anti -CD163 (CD163 Molecule, Hemoglobin Scavenger Receptor, M130, MM130, ScavengerReceptor Cysteine-rich Type 1 Protein M130) (HRP) - 139738-HRP from USBiological Life Science
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Anti -CD163 (CD163 Molecule, Hemoglobin Scavenger Receptor, M130, MM130, ScavengerReceptor Cysteine-rich Type 1 Protein M130) (PE) - 139738-PE from USBiological Life Science
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Anti -CD163 (Scavenger Receptor Cysteine-Rich Type 1 Protein M130, M130) - 227560 from USBiological Life Science
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Anti -CD163 (Scavenger Receptor Cysteine-Rich Type 1 Protein M130, M130) (Biotin) - 227561 from USBiological Life Science
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Anti -CD163 (Scavenger Receptor Cysteine-Rich Type 1 Protein M130, M130) (FITC) - 227562 from USBiological Life Science
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Anti -CD163 (Scavenger Receptor Cysteine-Rich Type 1 Protein M130, M130) (HRP) - 227563 from USBiological Life Science
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CD163 Antibody - abx102724 from Abbexa
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CD163 Antibody - abx110195 from Abbexa
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CD163 Antibody (Biotin) - abx105901 from Abbexa
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CD163 Antibody (FITC) - abx107317 from Abbexa
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CD163 Antibody (HRP) - abx108737 from Abbexa
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Anti-Cluster Of Differentiation (CD163) - 20-4056 from ARP American Research Products
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Scavenger receptor cysteine-rich type 1 protein M130, Polyclonal Antibody - MBS1491444 from MyBioSource
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Scavenger receptor cysteine-rich type 1 protein M130, Polyclonal Antibody - MBS1488763 from MyBioSource
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Scavenger receptor cysteine-rich type 1 protein M130, Polyclonal Antibody - MBS1489289 from MyBioSource
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Scavenger receptor cysteine-rich type 1 protein M130, Polyclonal Antibody - MBS1488581 from MyBioSource
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Cd163 Antibody - CSB-PA650452LA01MO from Cusabio
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