Cd163

Gene Symbol	Cd163
Entrez Gene	93671
Alt Symbol	CD163v2, CD163v3
Species	Mouse
Gene Type	protein-coding
Description	CD163 antigen
Other Description	scavenger receptor cysteine-rich type 1 protein M130
Swissprots	Q99MX8 A6H691 Q2VLH6 Q2VLH5
Accessions	EDK99729 Q2VLH6 AF274883 AAK16065 AK032012 BC144848 AAI44849 BC145793 AAI45794 DQ058616 AAY99763 DQ058617 AAY99764 XM_006506800 XP_006506863 NM_001170395 NP_001163866 NM_053094 NP_444324
Function	Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium- dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1 (By similarity). {ECO:0000250}.
Subcellular Location	Soluble CD163: Secreted {ECO:0000250}.
Tissue Specificity	Expressed in monocytes and mature macrophages such as Kupffer cells in the liver, red pulp macrophages in the spleen and mesenteric lymph nodes. {ECO:0000269|PubMed:11345593}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Mouse CD163 Gene ORF cDNA clone in cloning vector - MG51057-G from Sino Biological Species Mouse

Mouse CD163 Gene ORF cDNA clone expression plasmid, N-Myc tag - MG51057-NM from Sino Biological Species Mouse

Mouse CD163 Gene ORF cDNA clone expression plasmid, C-Myc tag - MG51057-CM from Sino Biological Species Mouse

Mouse CD163 Gene ORF cDNA clone expression plasmid, C-HA tag - MG51057-CY from Sino Biological Species Mouse

Mouse CD163 Gene ORF cDNA clone expression plasmid, N-His tag - MG51057-NH from Sino Biological Species Mouse

Mouse CD163 Gene ORF cDNA clone expression plasmid, N-HA tag - MG51057-NY from Sino Biological Species Mouse

Mouse CD163 Gene ORF cDNA clone expression plasmid - MG51057-UT from Sino Biological Species Mouse

Mouse CD163 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - MG51057-ACG from Sino Biological Species Mouse

Mouse CD163 Gene ORF cDNA clone expression plasmid, N-Flag tag - MG51057-NF from Sino Biological Species Mouse

Mouse CD163 Gene ORF cDNA clone expression plasmid, C-Flag tag - MG51057-CF from Sino Biological Species Mouse

Mouse CD163 Gene ORF cDNA clone expression plasmid - MG51057-G-N from Sino Biological Species Mouse

Mouse CD163 Gene ORF cDNA clone expression plasmid, C-His tag - MG51057-CH from Sino Biological Species Mouse

Mouse CD163 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - MG51057-ACR from Sino Biological Species Mouse

Mouse Cd163 ORF Clone(NM_053094.2) - CDCR264307 from Creative biogene Species Mouse

Mouse Cd163 ORF clone (NM_001170395.1) - CDCR043912 from Creative biogene Species Mouse

Mouse CD163 ORF clone (NM_053094.1) - CDCB157126 from Creative biogene Species Mouse

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