Fga

Gene Symbol	Fga
Entrez Gene	361969
Alt Symbol	Ac1873, Fba5e
Species	Rat
Gene Type	protein-coding
Description	fibrinogen alpha chain
Other Description	fibrinogen, A alpha polypeptide|fibrinogen, alpha polypeptide
Swissprots	P06399
Accessions	CAA60263 CAA60264 EDM00839 P06399 AY310161 AAP78769 BC098766 AAH98766 BC127465 AAI27466 FQ209852 M35601 AAA41158 XM_006232532 XP_006232594 XM_006232533 XP_006232595 NM_001008724 NP_001008724 NM_052797 NP_434684
Function	Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3- dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways. {ECO:0000250|UniProtKB:E9PV24}.
Subcellular Location	Secreted.
Top Pathways	Complement and coagulation cascades

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Fibrinogen Rat ELISA Kit - ab108845 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity = 3 ng/ml Range 3.125 ng/ml - 200 ng/ml

Fibrinogen Rat ELISA Kit - ab108846 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity = 0.3 µg/ml Range 0.31 µg/ml - 20 µg/ml

Fibrinogen Alpha (FGa), Rat, ELISA Kit - SEB154Ra from ARP American Research Products Category ELISA Kit Prices $742.00 Sizes 96 t Sensitivity 0.57ng/mL Range 1.56-100ng/mL

Fibrinogen alpha chain (FGA), Rat, ELISA Kit - E02F0366 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Fibrinogen alpha chain, Fga, Rat, ELISA Kit - E1237r from ARP American Research Products Category ELISA Kit Prices $656.00 Sizes 96 t Range 0.156-10 nmol/L

Rat Fga(Fibrinogen Alpha) ELISA Kit - E-EL-R0376 from Elabscience Category ELISA Kit Sensitivity 0.94 ng/mL Range 1.56—100 ng/mL

Rat Fga (Fibrinogen Alpha) CLIA Kit - E-CL-R0245 from Elabscience Category CLIA Kit Sensitivity 0.19 ng/mL Range Average Recovery (%)

fibrinogen total antigen assay - MBS135501 from MyBioSource Category ELISA Kit Sensitivity These studies are currently in progress. Please contact us for more information.

fibrinogen total antigen assay - MBS135508 from MyBioSource Category ELISA Kit Sensitivity The minimum detectable dose (MDD) was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates (range OD450: 0.071-0.078) and calculating the corresponding concentration. The MDD was 0.184 ng/ml.

Rat fibrinogen alpha chain (Fga) ELISA kit - CSB-E17440r from Cusabio Category ELISA Kit Sensitivity 0.078 Range Request Information

Rat Fibrinogen (FBG) ELISA Kit - ERF1040-1 from AssayPro Category ELISA Kit Range 0.313-20 ug/ml

Rat Fibrinogen (FBG) ELISA Kit - ERF2040-1 from AssayPro Category ELISA Kit Range 3.125-200 ng/ml

Rat Fga(Fibrinogen Alpha) ELISA Kit - E-EL-R0376 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.94 ng/mL Range 1.56~100 ng/mL

Rat Fga (Fibrinogen Alpha) CLIA Kit - E-CL-R0245 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 0.938ng/mL Range 1.563-100ng/mL

Rat Fibrinogen alpha chain ELISA Kit - abx256193 from Abbexa Category ELISA Kit Range 1.563 ng/ml - 100 ng/ml

Fibrinogen Alpha (FGa), Rat, ELISA Kit - DL-FGa-Ra from ARP American Research Products Category ELISA Kit Prices $715.00 Sizes 96 t Range 1.56-100 ng/mL

Fga (Fibrinogen Alpha), CLIA Kit - MBS2533193 from MyBioSource Category CLIA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313-20ng/mL

Rat Fibrinogen (total) ELISA Kit - ARG81085 from Arigo Biolaboratories Category ELISA Kit Sensitivity 0.184 ng/ml Range 3.125 - 800 ng/ml

Rat FGa ELISA Kit - abx573852 from Abbexa Category ELISA Kit Sensitivity 0.57 ng/ml Range 1.563 ng/ml - 100 ng/ml

Rat fibrinogen alpha chain (Fga) ELISA Kit - EKC39033 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.078 μg/ml Range 0.312 μg/ml-20 μg/ml

Rat Fibrinogen alpha chain ELISA Kit - EKE54263 from Biomatik Category ELISA Kit Prices $754.40, $3,206.20, $6,035.20 Sizes 96 t, 5x96t, 10x96t Range 0.78-50 ng/mL

Fga - EKR0424 from Nordic BioSite Sensitivity 0.938ng/ml Range 1.563-100ng/ml

Fga - EKR424 from Nordic BioSite Sensitivity 0.938ng/ml Range 1.563-100ng/ml

Fga ELISA Kit (Rat) : 96 Wells (OKEH02743) - OKEH02743 from Aviva Systems Biology Category ELISA Kit Prices $450.00 Sizes 96 wells Sensitivity < 0.22 ng/mL Range 0.78 - 50 ng/mL

Rat Fga ELISA Kit - E083373 from Biobool Category ELISA Kit

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