Fga

Gene Symbol	Fga
Entrez Gene	361969
Alt Symbol	Ac1873, Fba5e
Species	Rat
Gene Type	protein-coding
Description	fibrinogen alpha chain
Other Description	fibrinogen, A alpha polypeptide|fibrinogen, alpha polypeptide
Swissprots	P06399
Accessions	CAA60263 CAA60264 EDM00839 P06399 AY310161 AAP78769 BC098766 AAH98766 BC127465 AAI27466 FQ209852 M35601 AAA41158 XM_006232532 XP_006232594 XM_006232533 XP_006232595 NM_001008724 NP_001008724 NM_052797 NP_434684
Function	Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3- dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways. {ECO:0000250|UniProtKB:E9PV24}.
Subcellular Location	Secreted.
Top Pathways	Complement and coagulation cascades

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Rat Fibrinogen Alpha Protein - abx066568 from Abbexa Category Protein Source E.coli Species Rat

Rat Fibrinogen Alpha Protein - abx066569 from Abbexa Category Protein Source E.coli Species Rat

Fibrinogen Alpha (FGa), Rat - 20-7501 from ARP American Research Products Category Protein Prices $469.00 Sizes 50 µg Source E.coli Species Rat

Fibrinogen Alpha (FGa), Rat - 20-7502 from ARP American Research Products Category Protein Prices $469.00 Sizes 50 µg Source E.coli Species Rat

Native Rat Fibrinogen, FITC Labeled - Fga-63R from Creative Biomart Category Protein Source Rat plasma Species Rat

Native Rat Fibrinogen - Fga -67R from Creative Biomart Category Protein Source Rat plasma Species Rat

FITC Labeled Rat Fibrinogen - RFBGN-FITC from Molecular Innovations Category Protein Prices $500.00, $4,900.00 Sizes 1 mg, 10 mg Source Rat plasma Species Rat

Rat Fibrinogen - RFBGN from Molecular Innovations Category Protein Prices $250.00, $2,450.00 Sizes 1 mg, 10 mg Source Rat plasma Species Rat

Rat Fibrinogen (FBG) - PF10611 from AssayPro Prices $250.00 Sizes 1 mg Source Rat Plasma Species Rat

Recombinant Rat Fibrinogen alpha chain(Fga) - CSB-YP008607RA CSB-EP008607RA CSB-BP008607RA CSB-MP008607RA from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Rat

Fibrinogen Alpha (FGa), Recombinant Protein - MBS2010572 from MyBioSource Category Protein Prices $175.00, $360.00, $560.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Rat

Fibrinogen Alpha (FGa), Recombinant Protein - MBS2010851 from MyBioSource Category Protein Prices $175.00, $360.00, $560.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Rat

Fibrinogen alpha chain (Fga), Recombinant Protein - MBS1244208 from MyBioSource Category Protein Prices $1,560.00, $1,560.00, $1,785.00, $1,785.00, $2,685.00, $2,685.00, $3,125.00, $3,125.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Rat

FGA Recombinant Protein (OPCD03169) - OPCD03169 from Aviva Systems Biology Category Protein Source E.coli Species Rat

FGA Recombinant Protein (OPCD03172) - OPCD03172 from Aviva Systems Biology Category Protein Source E.coli Species Rat

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