ZW10

Gene Symbol ZW10
Entrez Gene 9183
Alt Symbol HZW10, KNTC1AP
Species Human
Gene Type protein-coding
Description zw10 kinetochore protein
Other Description ZW10 homolog, centromere/kinetochore protein|ZW10, kinetochore associated, homolog|centromere/kinetochore protein zw10 homolog|zeste white 10 homolog
Swissprots O43264 A1A528
Accessions EAW67229 O43264 AK300746 BAG62415 AK303871 BAG64809 AK312925 BAG35769 BC128264 AAI28265 BI547129 BM833775 BQ773926 DB506745 U54996 AAB88237 NM_004724 NP_004715
Function Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum. {ECO:0000269|PubMed:11590237, ECO:0000269|PubMed:15029241, ECO:0000269|PubMed:15094189, ECO:0000269|PubMed:15485811, ECO:0000269|PubMed:15824131}.
Subcellular Location Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Note=Dynamic pattern of localization during the cell cycle. In most cells at interphase, present diffusely in the cytoplasm. In prometaphase, associated with the kinetochore. At metaphase, detected both at the kinetochores and, most prominently, at the spindle, particularly at the spindle poles. In very early anaphase, detected on segregating kinetochores. In late anaphase and telophase, accumulates at the spindle midzone.
Tissue Specificity Widely expressed.

ZW10 (L-20) - sc-66692 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ZW10 (C-17) - sc-66691 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ZW10 (Y-15) - sc-66694 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ZW10 (Y-15): sc-66694. Western blot analysis of ZW10 expression in Ramos whole cell lysate.

ZW10 (3363C4a) - sc-81430 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
ZW10 (3363C4a): sc-81430 Western Blot analysis of human recombinant ZW10 fusion protein.

Anti-ZW10 antibody - ab21582 from Abcam

Prices $401.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ZW10 antibody (ab21582) at 1 µg/mlLane 1 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate (ab7899)Lane 2 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate (ab7899) with ZW10 peptide (ab23436) at 1 µg/mlLysates/proteins at 20 µg per lane.Secondary Goat polyclonal to Rabbit IgG(Alexa Fluor® 680) at 1/10,000 dilution Performed under reducing conditions.

Anti-ZW10 antibody - ab129575 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-ZW10 antibody (ab129575) at 1/100 dilution + mouse stomach tissue lysates at 35 µgdeveloped using the ECL technique

Anti-ZW10 antibody [3363C4a] - ab53676 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3363C4a
Staining of immunizing recombinant ZW10 fragment using anti-ZW10 antibody [3363C4a] (ab53676).

Anti-ZW10 Antibody - LS-C76945 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-ZW10 Antibody (aa59-88, AP) - LS-C218563 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZW10 Antibody (aa59-88, APC) - LS-C218564 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZW10 Antibody (aa59-88, Biotin) - LS-C218565 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZW10 Antibody (aa59-88, FITC) - LS-C218566 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZW10 Antibody (aa59-88, PE) - LS-C218568 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZW10 Antibody (aa59-88, Azide-free, HRP) - LS-C218567 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZW10 Antibody (aa58-88) - LS-C326758 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZW10 Antibody (clone 3363C4a) - LS-C184501 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 3363C4a
Western blot of immunized recombinant protein using ZW10 antibody.

Anti-ZW10 Antibody (aa71-120) - LS-C112183 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ZW10 antibody LS-C112183 Western blot of PANC1 cell lysate.

Anti-ZW10 Antibody (aa59-88) - LS-C160977 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ZW10 Antibody western blot of mouse stomach tissue lysates (35 ug/lane). The ZW10 antibody detected the ZW10 protein (arrow).

Anti-ZW10 Antibody (clone 3363C4a) - LS-C342542 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3363C4a
Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-ZW10 mAb.

ZW10 Antibody - NBP2-38644 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ZW10 Antibody [NBP2-38644] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4

ZW10 Antibody - NBP1-55252 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: ZW10 Antibody [NBP1-55252] - PANC1 cell lysate, concentration 0.2-1 ug/ml.

ZW10 Antibody - NBP2-38751 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ZW10 Antibody [NBP2-38751] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG

ZW10 Antibody (2E5) - H00009183-M05 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E5
Western Blot: ZW10 Antibody (2E5) [H00009183-M05] - Analysis of ZW10 expression in transfected 293T cell line by ZW10 monoclonal antibody (M05), clone 2E5. Lane 1: ZW10 transfected lysatE (88.8 KDa). Lane 2: Non-transfected lysate.

ZW10 Antibody - H00009183-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: ZW10 Antibody [H00009183-B01] - ZW10 MaxPab polyclonal antibody (B01), Lot # 08070 WULz. Western Blot analysis of ZW10 expression in human placenta.

ZW10 Antibody - H00009183-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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