ZW10

Gene Symbol	ZW10
Entrez Gene	9183
Alt Symbol	HZW10, KNTC1AP
Species	Human
Gene Type	protein-coding
Description	zw10 kinetochore protein
Other Description	ZW10 homolog, centromere/kinetochore protein|ZW10, kinetochore associated, homolog|centromere/kinetochore protein zw10 homolog|zeste white 10 homolog
Swissprots	O43264 A1A528
Accessions	EAW67229 O43264 AK300746 BAG62415 AK303871 BAG64809 AK312925 BAG35769 BC128264 AAI28265 BI547129 BM833775 BQ773926 DB506745 U54996 AAB88237 NM_004724 NP_004715
Function	Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum. {ECO:0000269|PubMed:11590237, ECO:0000269|PubMed:15029241, ECO:0000269|PubMed:15094189, ECO:0000269|PubMed:15485811, ECO:0000269|PubMed:15824131}.
Subcellular Location	Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Note=Dynamic pattern of localization during the cell cycle. In most cells at interphase, present diffusely in the cytoplasm. In prometaphase, associated with the kinetochore. At metaphase, detected both at the kinetochores and, most prominently, at the spindle, particularly at the spindle poles. In very early anaphase, detected on segregating kinetochores. In late anaphase and telophase, accumulates at the spindle midzone.
Tissue Specificity	Widely expressed.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ZW10 full length protein - ab132235 from Abcam Category Protein Source Wheat germ Species Human

ZW10 peptide - ab23436 from Abcam Category Peptide

ZW10 Antibody Blocking Peptide - LS-E4213 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ZW10 Antibody Blocking Peptide - LS-E21342 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ZW10 Protein - H00009183-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ZW10-Antibody-N-term-Blocking-Peptide - BP16473a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ZW10 Blocking Peptide - 33R-2055 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ZW10 - H00009183-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ZW10 - H00009183-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ZW10 fusion protein - ag19138 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human Centromere/kinetochore protein zw10 homolog(ZW10) - CSB-YP027154HU CSB-EP027154HU CSB-BP027154HU CSB-MP027154HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ZW10 - TP313297 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Centromere/kinetochore protein zw10 homolog (ZW10), Recombinant Protein - MBS1199367 from MyBioSource Category Protein Prices $1,595.00, $1,595.00, $1,825.00, $1,825.00, $2,760.00, $2,760.00, $3,200.00, $3,200.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

ZW10 Recombinant Protein Antigen - NBP2-38751PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ZW10 Recombinant Protein Antigen - NBP2-38644PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ZW10 Peptide, Human - M34GP18402H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Human ZW10 Protein, MYC/DDK-tagged - ZW10-1065H from Creative Biomart Category Protein Source HEK293 Species Human

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