Cd63

Gene Symbol Cd63
Entrez Gene 12512
Alt Symbol C75951, ME491, Tspan30
Species Mouse
Gene Type protein-coding
Description CD63 antigen
Other Description melanoma 1 antigen
Swissprots P41731
Accessions EDL24631 P41731 AF159427 AAD43135 AK028220 BAC25821 AK146618 BAE27307 AK150647 BAE29734 AK151702 BAE30625 AK151963 BAE30834 AK152072 BAE30925 AK152372 BAE31162 AK159875 BAE35447 AK163785 BAE37493 AK166373 AK166543 BAE38843 AK166766 BAE39004 AK170344 BAE41734 AK178060 AK178582 AK182243 AK184072 AK184717 AK188607 AK188949 AK208438 AK210314 AK211715 AK216882 BC008108 AAH08108 BC012212 AAH12212 BC083161 AAH83161 BP769648 BY164291 CF355016 CJ210573 CT010179 CAJ18387 D16432 BAA03904 NM_001042580 NP_001036045 NM_001282966 NP_001269895 NM_007653 NP_031679
Function Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli. {ECO:0000269|PubMed:19075008, ECO:0000269|PubMed:2
Subcellular Location Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Endosome, multivesicular body {ECO:0000250}. Melanosome {ECO:0000250}. Note=Also found in Weibel-Palade bodies of endothelial cells. Located in platelet dense granules. Detected in a subset of pre-melanosomes. Detected on intralumenal vesicles (ILVs) within multivesicular bodies (By similarity). {ECO:0000250}.
Tissue Specificity Ubiquitous. Strongly expressed in kidney. Detected in spleen, bone marrow, peripheral blood mononuclear cells and macrophages.
Top Pathways Lysosome, Proteoglycans in cancer

CD63 (T-14) - sc-25183 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CD63 (Y-17) - sc-25184 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CD63 Antibody (7G4.2E8) - NBP2-36567 from Novus Biologicals

Prices $99.00, $279.00
Sizes 25 µg, 100 µg
Host Rat
Clonality Monoclonal
Clone 7G4.2E8
Western Blot: CD63 Antibody (7G4.2E8) [NBP2-36567] - Western blot analysis of mouse CD63 on recombinant mouse CD63 and mouse kidney lysate.

CD63 Antibody (446703) [Unconjugated] - MAB5417 from Novus Biologicals

Prices $99.00, $259.00
Sizes 25 µg, 100 µg
Host Rat
Clonality Monoclonal
Clone 446703
HEK293 human embryonic kidney cell line transfected with either (A) mouse CD63 or (B) irrelevant transfectants and eGFP were stained with Rat Anti-Mouse CD63 Monoclonal Antibody (Catalog # MAB5417) followed by Allophycocyanin-conjugated Anti-Rat IgG Secondary Antibody (Catalog # F0113). Quadrant markers were set based on control antibody staining (Catalog # MAB005). View our protocol for Staining Membrane-associated Proteins.

CD63 Antibody (OACA00261) - OACA00261 from Aviva Systems Biology

Prices $270.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

CD63 Antibody (OACA00262) - OACA00262 from Aviva Systems Biology

Prices $270.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

CD63 Antibody (OACA00263) - OACA00263 from Aviva Systems Biology

Prices $270.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

CD63 Antibody (OACA00264) - OACA00264 from Aviva Systems Biology

Prices $270.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

CD63 antigen Antibody - abx109635 from Abbexa

Prices $490.00, $490.00, $490.00, $490.00
Sizes 10 μl, 50 μl, 100 μl, 200 μl
Host Rabbit
Clonality Polyclonal

CD63 antigen Antibody (Biotin) - abx105248 from Abbexa

Prices $490.00, $490.00, $490.00, $490.00
Sizes 10 μl, 50 μl, 100 μl, 200 μl
Host Rabbit
Clonality Polyclonal

CD63 antigen Antibody (FITC) - abx106666 from Abbexa

Prices $490.00, $490.00, $490.00, $490.00
Sizes 10 μl, 50 μl, 100 μl, 200 μl
Host Rabbit
Clonality Polyclonal

CD63 antigen Antibody (HRP) - abx108083 from Abbexa

Prices $490.00, $490.00, $490.00, $490.00
Sizes 10 μl, 50 μl, 100 μl, 200 μl
Host Rabbit
Clonality Polyclonal

CD63 antibody - AM26556AF-N from Acris Antibodies

Prices $290.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone R5G2
Western blot analysis of mouse CD63 expression in GFP-tagged mouse CD63 transfected 293T (2, 4) and GFP transfected 293T (1, 3) using anti-GFP antibody (clone 1E4, lane 1 and 2) or anti-mouse CD63 (clone R5G2, lane 3 and 4, AM26556AF-N).

APC anti-mouse CD63 Antibody - 143905 from Biolegend

Prices $115.00, $265.00
Sizes 25 µg, 100 µg
Host Rat
Clone NVG-2
bEND.3 cells were stained with CD63 (clone NVG-2) APC (filled histogram) or rat IgG2a, κ APC isotype control (open histogram).

APC/Cy7 anti-mouse CD63 Antibody - 143907 from Biolegend

Prices $135.00, $295.00
Sizes 25 µg, 100 µg
Host Rat
Clone NVG-2
bEND.3 cells were stained with CD63 (clone NVG-2) APC/Cy7 (filled histogram) or rat IgG2a, κ APC/Cy7 isotype control (open histogram).

PE anti-mouse CD63 Antibody - 143903 from Biolegend

Prices $105.00, $245.00
Sizes 25 µg, 100 µg
Host Rat
Clone NVG-2
bEnd.3, mouse endothelial cells were stained with CD63 (clone NVG-2) PE (filled histogram) or rat IgG2a, κ PE isotype control (open histogram).

PE/Cy7 anti-mouse CD63 Antibody - 143909 from Biolegend

Prices $135.00, $295.00
Sizes 25 µg, 100 µg
Host Rat
Clone NVG-2
bEND.3 cells were stained with CD63 (clone NVG-2) PE/Cy7 (filled histogram) or rat IgG2a, κ PE/Cy7 isotype control (open histogram).

PE/Dazzle™ 594 anti-mouse CD63 Antibody - 143913 from Biolegend

Prices $135.00, $295.00
Sizes 25 µg, 100 µg
Host Rat
Clone NVG-2
bEND.3 cells were stained with CD63 (clone NVG-2) PE/ Dazzle™ 594 (filled histogram) or rat IgG2a, κ PE/ Dazzle™ 594 isotype control (open histogram).

PerCP/Cy5.5 anti-mouse CD63 Antibody - 143911 from Biolegend

Prices $135.00, $295.00
Sizes 25 µg, 100 µg
Host Rat
Clone NVG-2
bEND.3 cells were stained with CD63 (clone NVG-2) PerCp/Cy5.5 (filled histogram) or rat IgG2a, κ PerCp/Cy5.5 isotype control (open histogram).

Purified anti-mouse CD63 Antibody - 143901 from Biolegend

Prices $75.00, $175.00
Sizes 25 µg, 100 µg
Host Rat
Clone NVG-2
bEnd.3, mouse endothelial cells were stained with purified CD63 (clone NVG-2) (filled histogram) or rat IgG2a, κ isotype control (open histogram), followed by anti-rat IgG PE.

BD Pharmingen™ Purified Rat Anti-Mouse CD63 - 564221 from BD Biosciences

Prices $110.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone NVG-2

BD Pharmingen™ PE Rat Anti-Mouse CD63 - 564222 from BD Biosciences

Prices $155.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone NVG-2

CD63 antigen, Polyclonal Antibody - MBS1490262 from MyBioSource

Prices $160.00, $235.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

CD63 antigen, Polyclonal Antibody - MBS1488249 from MyBioSource

Prices $160.00, $235.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal
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