ASGR2

Gene Symbol ASGR2
Entrez Gene 433
Alt Symbol ASGP-R2, ASGPR2, CLEC4H2, HBXBP, HL-2
Species Human
Gene Type protein-coding
Description asialoglycoprotein receptor 2
Other Description C-type lectin domain family 4 member H2|HBxAg-binding protein|hepatic lectin H2
Swissprots A8MT12 D3DTN0 D3DTM9 P07307 A6NLV8 Q03969 O00448
Accessions EAW90259 EAW90260 EAW90261 EAW90262 EAW90263 EAW90264 P07307 AF529374 AAQ09608 AK303787 BAG64744 AK310123 BC017251 AAH17251 BM561839 BX483468 DC315727 DQ892652 ABM83578 DQ895891 ABM86817 M11025 AAB59519 U97197 AAB58308 X55283 CAA38997 X55284 XM_005256648 XP_005256705 XM_006721524 XP_006721587 XM_006721525 XP_006721588 XM_006721526 XP_006721589 XM_011523862 XP_011522164 XM_011523863 XP_011522165 XM_011523864 XP_011522166 XM_011523865 XP_011522167 XM_011523866 XP_011522168 NM_001181 NP_001172 NM_001201352 NP_001188281 NM_080912 NP_550434 NM_080913 NP_550435 NM_080914 NP_550436
Function Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
Subcellular Location Membrane; Single-pass type II membrane protein.
Tissue Specificity Expressed exclusively in hepatic parenchymal cells.
Top Pathways Thyroid hormone synthesis

ASGPR2 (B-4) - sc-377113 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ASGPR2 (B-4): sc-377113. Western blot analysis of ASGPR2 expression in non-transfected: sc-117752 (A) and human ASGPR2 transfected: sc-172363 (B) 293T whole cell lysates.

ASGPR2 (G-17) - sc-13472 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ASGPR2 (G-17): sc-13472. Immunoperoxidase staining of formalin fixed, paraffin-embedded human liver tissue showing cytoplasmic and membrane staining of hepatocytes.

ASGPR2 (H-55) - sc-292647 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ASGPR2 (H-55): sc-292647. Western blot analysis of ASGPR2 expression in A549 (A) and MCF7 (B) whole cell lysates.

ASGPR2 (K-21) - sc-130964 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Rabbit
Clonality Polyclonal
ASGPR2 (K-21): sc-130964. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human intestine tissue showing cytoplasmic localization.

ASGPR2 (N-17) - sc-13471 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ASGPR2 (3-YD7) - sc-134273 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
ASGPR2 (3-YD7): sc-134273. Western blot analysis of ASGPR2 expression in K-562 whole cell lysate.

Anti-Asialoglycoprotein Receptor 2 antibody - ab77032 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-Asialoglycoprotein Receptor 2 antibody (ab77032) at 5 µg/ml + immunogen (GST-tagged full length protein) at 0.2 µgSecondaryGoat Anti-Mouse IgG (H&L) HRP-conjugated at 1/5000 dilution

Anti-Asialoglycoprotein Receptor 2 antibody - ab37470 from Abcam

Prices $372.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-Asialoglycoprotein Receptor 2 antibody - ab171794 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Asialoglycoprotein Receptor 2 antibody (ab171794) at 1 µg/mlLane 1 : Asialoglycoprotein Receptor 2 transfected 293T lysateLane 2 : Non-transfected 293T lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP conjugated at 1/2500 dilutiondeveloped using the ECL technique

Anti-Asialoglycoprotein Receptor 2 antibody [2A12] - ab139298 from Abcam

Prices $384.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2A12
ICC/IF image of ab139298 stained HepG2 cells.  The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab139298 at 1/100 dilution overnight at +4°C. The secondary antibody (green) was DyLight® 488 Goat anti-Mouse IgG (H+L) (ab96879) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-Asialoglycoprotein Receptor 2 antibody [4B6] - ab156792 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4B6
All lanes : Anti-Asialoglycoprotein Receptor 2 antibody [4B6] (ab156792) at 1/4000 dilutionLane 1 : HEK293T cells transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cells transfected with pCMV6-ENTRY Asialoglycoprotein Receptor 2 cDNALysates/proteins at 5 µg per lane.

Anti-Asialoglycoprotein Receptor 2 antibody [EPR16974] - ab197032 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16974
All lanes : Anti-Asialoglycoprotein Receptor 2 antibody [EPR16974] (ab197032) at 1/1000 dilutionLane 1 : Human fetal liver lysateLane 2 : MCF-7 (Human breast adenocarcinoma cell line) whole cell lysateLane 3 : K562 (Human chronic myelogenous leukemia cells from bone marrow) whole cell lysateLane 4 : Jurkat (Human T cell leukemia cells from peripheral blood) whole cell lysateLane 5 : HeLa (Human epithetial cells from cervix adenocarcinoma) whole cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilutiondeveloped using the ECL technique

Anti-Asialoglycoprotein Receptor 2 antibody [EPR16975] - ab200196 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16975
All lanes : Anti-Asialoglycoprotein Receptor 2 antibody [EPR16975] (ab200196) at 1/5000 dilutionLane 1 : Human fetal liver lysateLane 2 : K562 (Human chronic myelogenous leukemia cells from bone marrow) whole cell lysateLane 3 : HeLa (Human epithelial cells from cervix adenocarcinoma) whole cell lysateLane 4 : MCF7 (Human breast adenocarcinoma cell line) whole cell lysateLysates/proteins at 10 µg per lane.SecondaryAnti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Anti-ASGR2 Antibody (aa71-120) IHC-plus™ - LS-B9655 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ASGR2 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9655 concentration 5 ug/ml.

Anti-ASGR2 Antibody (aa1-288) - LS-C126945 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-ASGR2 Antibody - LS-C306405 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-ASGR2 Antibody (aa106-155) - LS-C31551 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ASGR2 antibody LS-C31551 was used in IHC to stain formalin-fixed, paraffin-embedded human spleen.

Anti-ASGR2 Antibody (clone 4B6) - LS-C337843 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4B6
Immunofluorescent staining of HeLa cells using anti-ASGR2 mouse monoclonal antibody.

Anti-ASGR2 Antibody (clone 1D7) - LS-C196698 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D7
Western Blot analysis of ASGR2 expression in transfected 293T cell line by ASGR2 monoclonal antibody (M05), clone 1D7.Lane 1: ASGR2 transfected lysate (Predicted MW: 32.6 KDa).Lane 2: Non-transfected lysate.

Anti-ASGR2 Antibody (clone 2A12) - LS-C174143 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2A12
IHC of paraffin-embedded Human lymph node tissue using anti-ASGR2 mouse monoclonal antibody.

Asialoglycoprotein Receptor 2 Antibody - NBP1-85578 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Asialoglycoprotein Receptor 2 Antibody [NBP1-85578] - Analysis in human cell line CACO-2.

Asialoglycoprotein Receptor 2 Antibody - NBP1-52958 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Asialoglycoprotein Receptor 2 Antibody [NBP1-52958] - Fetal Lung tissue at a concentration of 0.5ug/ml.

Asialoglycoprotein Receptor 2 Antibody - NBP1-54888 from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Asialoglycoprotein Receptor 2 Antibody [NBP1-54888] - Sample Tissue: Human HepG2 Antibody Dilution: 1.0 ug/ml

Asialoglycoprotein Receptor 2 Antibody - NBP1-85579 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Asialoglycoprotein Receptor 2 Antibody [NBP1-85579] - Staining of human liver shows moderate cytoplasmic positivity in hepatocytes.

Asialoglycoprotein Receptor 2 Antibody (1D7) - H00000433-M05 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D7
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