GJA1

Gene Symbol GJA1
Entrez Gene 2697
Alt Symbol AVSD3, CMDR, CX43, GJAL, HLHS1, HSS, ODDD
Species Human
Gene Type protein-coding
Description gap junction protein, alpha 1, 43kDa
Other Description connexin 43|connexin-43|gap junction 43 kDa heart protein|gap junction alpha-1 protein
Swissprots P17302 Q9Y5I8 Q6FHU1 B2R5U9
Accessions AAD37802 EAW48178 P17302 AK223289 BAD97009 AK294670 BAG57837 AK295460 BAG58393 AK297402 BAG59841 AK297761 BAG60109 AK297764 BAG60112 AK309377 AK309490 AK312324 BAG35246 AW664595 BC026329 AAH26329 BP226987 CR541660 CAG46461 DQ893649 ABM84575 DQ895611 ABM86537 M65188 AAA52131 X52947 CAA37122 NM_000165 NP_000156
Function Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:22411987}; Multi-pass membrane protein {ECO:0000269|PubMed:22411987}. Cell junction, gap junction {ECO:0000269|PubMed:22411987}.
Tissue Specificity Expressed in the heart and fetal cochlea. {ECO:0000269|PubMed:11741837}.
Top Pathways Gap junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Human-GJA1-cDNA-Clone - DC05621 from Abgent, a WuXi AppTec company

Prices $515.70
Sizes 10 µg
Species Human
Accession BC026329

Human Connexin 43/GJA1 (NP_000156) VersaClone cDNA - RDC0534 from R&D Systems

Prices $199.00
Sizes 10 µg
Species Human

GJA1 - MBS1267643 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC026329

Human GJA1 ORF Clone(NM_000165.3) - CDCL164664 from Creative Biomart

Species Human
Accession NM_000165.3

Human GJA1 ORF Clone(NM_000165.3) - CDCR278959 from Creative Biomart

Species Human
Accession NM_000165.3

Human GJA1 ORF Clone(NM_000165.3) - CDCR278960 from Creative Biomart

Species Human
Accession NM_000165.3

Human GJA1 ORF Clone(NM_000165.3) - CDCR278959 from Creative biogene

Species Human

Human GJA1 ORF Clone (BC026329) - CDCS405471 from Creative biogene

Species Human
Accession P17302
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