GJA1

Gene Symbol GJA1
Entrez Gene 2697
Alt Symbol AVSD3, CMDR, CX43, GJAL, HLHS1, HSS, ODDD
Species Human
Gene Type protein-coding
Description gap junction protein, alpha 1, 43kDa
Other Description connexin 43|connexin-43|gap junction 43 kDa heart protein|gap junction alpha-1 protein
Swissprots P17302 Q9Y5I8 Q6FHU1 B2R5U9
Accessions AAD37802 EAW48178 P17302 AK223289 BAD97009 AK294670 BAG57837 AK295460 BAG58393 AK297402 BAG59841 AK297761 BAG60109 AK297764 BAG60112 AK309377 AK309490 AK312324 BAG35246 AW664595 BC026329 AAH26329 BP226987 CR541660 CAG46461 DQ893649 ABM84575 DQ895611 ABM86537 M65188 AAA52131 X52947 CAA37122 NM_000165 NP_000156
Function Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:22411987}; Multi-pass membrane protein {ECO:0000269|PubMed:22411987}. Cell junction, gap junction {ECO:0000269|PubMed:22411987}.
Tissue Specificity Expressed in the heart and fetal cochlea. {ECO:0000269|PubMed:11741837}.
Top Pathways Gap junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Connexin 43 / GJA1 (phospho S368) peptide - ab197598 from Abcam

Category Peptide
Prices $181.00
Sizes 50 µg

Connexin 43 / GJA1 peptide - ab171366 from Abcam

Category Peptide
Prices $285.00
Sizes 100 µg

Human Connexin 43 / GJA1 peptide - ab56616 from Abcam

Category Peptide

Human Connexin 43 / GJA1 peptide - ab92658 from Abcam

Category Peptide

GJA1 / CX43 / Connexin 43 Antibody Blocking Peptide - LS-E3804 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

GJA1 / CX43 / Connexin 43 Antibody Blocking Peptide - LS-E13113 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

GJA1 / CX43 / Connexin 43 Antibody Blocking Peptide - LS-E13114 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

GJA1 / CX43 / Connexin 43 Antibody Blocking Peptide - LS-E27042 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

GJA1 / CX43 / Connexin 43 Antibody Blocking Peptide - LS-E29655 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

GJA1 / CX43 / Connexin 43 Antibody Blocking Peptide - LS-E29656 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

Connexin 43/GJA1 Peptide - P0545 from Novus Biologicals

Category Peptide
Species Human

Connexin-43-Antibody-N-term-Blocking-peptide - BP1541b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Human GJA1 GJAL protein - orb245698 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Human

GJA1 Blocking Peptide - 33R-3592 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

GJA1 Blocking Peptide - 33R-5566 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

Connexin 43 Blocking Peptide - abx062665 from Abbexa

Category Peptide
Species Human, Mouse, Rat, Bovine, Chicken, Dog, Rabbit

Connexin 43 Blocking Peptide - abx062124 from Abbexa

Category Peptide
Species Human, Mouse, Rat, Bovine, Chicken, Dog, Monkey, Pig, Rabbit

Human Connexin 43 Protein - abx066106 from Abbexa

Category Protein
Source E.coli
Species Human

Connexin 43 / Gja1 Peptide - AC21-1865-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

GJA1 Peptide - 46-995P from ProSci

Category Peptide
Species Rat

Connexin 43 fusion protein - ag6698 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

Connexin 43 (phospho-Ser367) Antibody Blocking Peptide - GWB-7CEEB0 from Genway Biotech

Category Peptide
Prices $138.00
Sizes 100 µg

Recombinant Connexin 43 (CX43) - RPA277Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Connexin 43 (CX43) - RPA277Mu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse

Recombinant Connexin 43 (CX43) - RPA277Mu02 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse
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