HES1

Gene Symbol HES1
Entrez Gene 3280
Alt Symbol HES-1, HHL, HRY, bHLHb39
Species Human
Gene Type protein-coding
Description hes family bHLH transcription factor 1
Other Description class B basic helix-loop-helix protein 39|hairy homolog|hairy-like protein|transcription factor HES-1
Swissprots Q14469 Q6FHB2
Accessions AAA65220 EAW78058 Q14469 AF264785 AAF73060 AI370424 AK000415 BAA91149 AK300482 BAG62198 BC005178 AAH05178 BC039152 AAH39152 BC156516 AAI56517 BC172546 AAI72546 CR541843 CAG46641 DQ891328 ABM82254 DQ893354 ABM84280 DQ896673 ABM87672 DW424342 NM_005524 NP_005515
Function Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage. {ECO:0000250, ECO:0000269|PubMed:18550849}.
Subcellular Location Nucleus.
Top Pathways Notch signaling pathway, Maturity onset diabetes of the young, Fanconi anemia pathway

HES1 CRISPR/Cas9 KO Plasmid (h) - sc-400387 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HES1 HDR Plasmid (h) - sc-400387-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HES1 Double Nickase Plasmid (h) - sc-400387-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HES1 Double Nickase Plasmid (h2) - sc-400387-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HES1 CRISPR Activation Plasmid (h) - sc-400387-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HES1 CRISPR Activation Plasmid (h2) - sc-400387-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HES1 Lentiviral Activation Particles (h) - sc-400387-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HES1 Lentiviral Activation Particles (h2) - sc-400387-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HES1 siRNA (h) - sc-37938 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HES1 shRNA Plasmid (h) - sc-37938-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HES1 shRNA (h) Lentiviral Particles - sc-37938-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU013081 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9992 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9992 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03092 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03092

HES1 siRNA (Human) - CRH2243 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HES-1 RNAi - H00003280-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

HES1 - MBS8222907 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human HES1 (NM_005524.3) - SHH311677 from Creative biogene

Category siRNA
Species Reactivities Human

Human HES1 siRNA - orb262745 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HES1 shRNA Plasmid (Human) - CHH2243 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HES1 miRNA 3'UTR clone - MiUTR3H-00990 from Creative biogene

Species Reactivities Human
Search more