MSH3

Gene Symbol	MSH3
Entrez Gene	4437
Alt Symbol	DUP, MRP1
Species	Human
Gene Type	protein-coding
Description	mutS homolog 3
Other Description	DNA mismatch repair protein Msh3|divergent upstream protein|hMSH3|mismatch repair protein 1
Swissprots	Q6PJT5 Q86UQ6 A1L482 A6NMM6 A1L480 Q92867 P20585
Accessions	AAP13535 BAD27111 EAW95861 EAW95862 P20585 AA601983 AI817671 AK289856 BAF82545 BC004177 BC011817 AAH11817 BC017273 BC098436 BC130434 AAI30435 BC130436 AAI30437 BF593920 J04810 AAB47281 U61981 AAB06045 NM_002439 NP_002430
Function	Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion- deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.
Top Pathways	Mismatch repair, Colorectal cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MSH3 peptide - ab74606 from Abcam Category Peptide

MSH3-Antibody-Center-Blocking-Peptide - BP16542c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MSH3-Antibody-Center-Blocking-Peptide - BP2846c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MSH3 fusion protein - ag18060 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

MSH3 fusion protein - Ag19187 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human MSH3 - MSH3-494H from Creative Biomart Category Protein Source Mammalian Cells Species Human

MSH3 Blocking Peptide - CBP4099 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

MSH3 (A80) Peptide - BS2419P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human DNA mismatch repair protein Msh3(MSH3) ,partial - CSB-YP015029HU CSB-EP015029HU CSB-BP015029HU CSB-MP015029HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MSH3 Protein - NBP1-84966PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

MSH3 Protein - NBP1-84965PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

MSH3 Blocking Peptide - abx162592 from Abbexa Category Peptide Species Human

MSH3 Peptide, Human - M34GP09820H from Creative Peptides Category Peptide Source Synthetic. Species Human

DNA mismatch repair protein Msh3 (MSH3), partial, Recombinant Protein - MBS965576 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

MSH3 peptide - orb256986 from Biorbyt Category Peptide

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