MSH3

Gene Symbol MSH3
Entrez Gene 4437
Alt Symbol DUP, MRP1
Species Human
Gene Type protein-coding
Description mutS homolog 3
Other Description DNA mismatch repair protein Msh3|divergent upstream protein|hMSH3|mismatch repair protein 1
Swissprots Q6PJT5 Q86UQ6 A1L482 A6NMM6 A1L480 Q92867 P20585
Accessions AAP13535 BAD27111 EAW95861 EAW95862 P20585 AA601983 AI817671 AK289856 BAF82545 BC004177 BC011817 AAH11817 BC017273 BC098436 BC130434 AAI30435 BC130436 AAI30437 BF593920 J04810 AAB47281 U61981 AAB06045 NM_002439 NP_002430
Function Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion- deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.
Top Pathways Mismatch repair, Colorectal cancer

MSH3 CRISPR/Cas9 KO Plasmid (h) - sc-403422 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSH3 HDR Plasmid (h) - sc-403422-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSH3 Double Nickase Plasmid (h) - sc-403422-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSH3 Double Nickase Plasmid (h2) - sc-403422-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSH3 CRISPR Activation Plasmid (h) - sc-403422-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSH3 CRISPR Activation Plasmid (h2) - sc-403422-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSH3 Lentiviral Activation Particles (h) - sc-403422-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSH3 Lentiviral Activation Particles (h2) - sc-403422-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSH3 siRNA (h) - sc-35971 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MSH3 shRNA Plasmid (h) - sc-35971-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MSH3 shRNA (h) Lentiviral Particles - sc-35971-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MSH3 RNAi - H00004437-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU057111 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® esiRNA - EHU057951 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN14643 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14643 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07767 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07767

MSH3 siRNA (Human) - CRH2969 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Msh3 (NM_002439.4) - SHH345628 from Creative biogene

Category siRNA
Species Reactivities Human

Human MSH3 siRNA - orb263471 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MSH3 shRNA Plasmid (Human) - CHH2969 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MSH3 miRNA 3'UTR clone - MiUTR3H-03712 from Creative biogene

Species Reactivities Human
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