NAIP

Gene Symbol	NAIP
Entrez Gene	4671
Alt Symbol	BIRC1, NLRB1, psiNAIP
Species	Human
Gene Type	protein-coding
Description	NLR family, apoptosis inhibitory protein
Other Description	baculoviral IAP repeat-containing protein 1|neuronal apoptosis inhibitory protein|nucleotide-binding oligomerization domain, leucine rich repeat and BIR domain containing 1|psi neuronal apoptosis inhibitory protein
Swissprots	Q99796 E9PHD1 Q13730 O75857 B9EG72 Q13075 Q8TDZ4 Q59GI6
Accessions	AAC52047 AAC62261 EAW50510 Q13075 AB048534 BAB87181 AB209123 BAD92360 AK124511 AK295115 BAG58144 AK309627 AK311046 BC136273 AAI36274 BC143761 AAI43762 DQ786305 U19251 AAC52045 XM_005248523 XP_005248580 XM_005248524 XP_005248581 XM_005276800 XP_005276857 XM_005276801 XP_005276858 XM_005276802 XP_005276859 XM_006714626 XP_006714689 XM_006714629 XP_006714692 XM_006714630 XP_006714693 XM_006725453 XP_006725516 XM_006725456 XP_006725519 XM_006725457 XP_006725520 XM_006725458 XP_006725521 XM_006725459 XP_006725522 XM_006726219 XP_006726282 XM_006726222 XP_006726285 XM_011543409 XP_011541711 XM_011543410 XP_011541712 XM_011543411 XP_011541713 XM_011543412 XP_011541714 XM_011543413 XP_011541715 XM_011546973 XP_011545275 XM_011546974 XP_011545276 XM_011546975 XP_011545277 XM_011546976 XP_011545278 XM_011546977 XP_011545279 XM_011546978 XP_011545280 XM_011546979 XP_011545281 XM_011547345 XP_011545647 XM_011547346 XP_011545648 XM_011547347 XP_011545649 XM_011547348 XP_011545650 XM_011547349 XP_011545651 NM_004536 NP_004527 NM_022892 NP_075043
Function	Anti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7 and CASP9. Can inhibit the autocleavage of pro-CASP9 and cleavage of pro-CASP3 by CASP9. Capable of inhibiting CASP9 autoproteolysis at 'Asp-315' and decreasing the rate of auto proteolysis at 'Asp-330'. Acts as a mediator of neuronal survival in pathological conditions. Prevents motor- neuron apoptosis induced by a variety of signals. Possible role in the prevention of spinal muscular atrophy that seems to be caused by inappropriate persistence of motor-neuron apoptosis: mutated or deleted forms of NAIP have been found in individuals with severe spinal muscular atrophy.
Tissue Specificity	Expressed in motor neurons, but not in sensory neurons. Found in liver and placenta, and to a lesser extent in spinal cord.
Top Pathways	NOD-like receptor signaling pathway, Legionellosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human BIRC1 / NAIP ELISA Kit (Sandwich ELISA) - LS-F4669 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 0.058 ng/ml Range 0.156-10 ng/ml

Human NAIP ELISA Kit - abx054526 from Abbexa Category ELISA Kit

Human NAIP ELISA Kit - abx152452 from Abbexa Category ELISA Kit Sensitivity 0.058 ng/ml Range 0.156 ng/ml - 10 ng/ml

Baculoviral IAP repeat-containing protein 1, NAIP, Human, ELISA Kit - E1524h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

Neuronal Apoptosis Inhibitory Protein, NAIP, Human, ELISA Kit - E-EL-H1900 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Neuronal Apoptosis Inhibitory Protein (NAIP), Human, ELISA Kit - SEB524Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 0.058ng/mL Range 0.156-10ng/mL

Neuronal Apoptosis Inhibitory Protein, NAIP, Rabbit, ELISA Kit - E-EL-RB1428 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Neuronal Apoptosis Inhibitory Protein, NAIP, Chicken, ELISA Kit - E-EL-Ch1185 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Neuronal Apoptosis Inhibitory Protein, NAIP, Porcine, ELISA Kit - E-EL-P1132 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Neuronal Apoptosis Inhibitory Protein, NAIP, Guinea Pig, ELISA Kit - E-EL-GP0389 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Neuronal Apoptosis Inhibitory Protein, NAIP, Monkey, ELISA Kit - E-EL-MK0265 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human NAIP ELISA Kit - HN0077 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine NAIP ELISA Kit - AN0077 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

NAIP, ELISA Kit - MBS2504991 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

NAIP, ELISA Kit - MBS2506877 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

NAIP, ELISA Kit - MBS2506880 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156--10ng/mL

NAIP, ELISA Kit - MBS2504096 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 37.5pg/mL Range 62.5-4000pg/mL

NAIP, ELISA Kit - MBS2502594 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

NAIP, ELISA Kit - MBS2511300 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

Human NAIP(Neuronal Apoptosis Inhibitory Protein) ELISA Kit - E-EL-H1900 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

Human NAIP (Neuronal Apoptosis Inhibitory Protein) CLIA Kit - E-CL-H1174 from Elabscience Category CLIA Kit Sensitivity 18.75 pg/mL Range Average Recovery (%)

Neuronal apoptosis inhibitory protein, ELISA Kit - MBS727816 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Neuronal apoptosis inhibitory protein, ELISA Kit - MBS726047 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Neuronal apoptosis inhibitory protein, ELISA Kit - MBS727839 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Neuronal Apoptosis Inhibitory Protein, ELISA Kit - MBS030496 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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