Gene Symbol | Fbxo32 |
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Entrez Gene | 67731 |
Alt Symbol | 4833442G10Rik, AI430017, ATROGIN1, Gm20361, MAFbx |
Species | Mouse |
Gene Type | protein-coding |
Description | F-box protein 32 |
Other Description | F-box only protein 32|atrogin 1|muscle atrophy F-box protein |
Swissprots | Q9CPU7 |
Accessions | EDL29301 Q9CPU7 AF441120 AAL49563 AK014612 BAB29463 AK014793 BAB29555 AK033632 AK033658 AK190642 AK202405 AK216124 BB838158 BC027211 AAH27211 BU921446 NM_026346 NP_080622 |
Function | Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1 (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Shuttles between Cytoplasm and the nucleus. {ECO:0000250}. |
Tissue Specificity | Specifically expressed in cardiac and skeletal muscle. |
Recombinant Mouse F-box only protein 32(Fbxo32) - CSB-YP887410MO CSB-EP887410MO CSB-BP887410MO CSB-MP887410MO from Cusabio
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Recombinant Mouse FBXO32 Protein - FBXO32-5744M from Creative Biomart
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F-box only protein 32 (Fbxo32), Recombinant Protein - MBS1485450 from MyBioSource
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