CTNNA1

Gene Symbol	CTNNA1
Entrez Gene	1495
Alt Symbol	CAP102
Species	Human
Gene Type	protein-coding
Description	catenin (cadherin-associated protein), alpha 1, 102kDa
Other Description	alpha E-catenin|alpha-E-catenin|alpha-catenin|alphaE-catenin|cadherin-associated protein,102kDa|catenin alpha-1|renal carcinoma antigen NY-REN-13
Swissprots	Q8N1C0 Q12795 P35221
Accessions	AAC99459 AAW56940 EAW62122 EAW62123 EAW62124 P35221 AI078507 AK055751 AK094151 BAG52830 AK296708 BAG59301 AK300439 BAG62162 AK304267 BAG65130 AU141929 BC000385 AAH00385 BC031262 AAH31262 BU624488 D13866 BAA02979 D14705 BAA03530 DA349847 DC369291 DQ891250 ABM82176 DQ894435 ABM85361 HQ589335 AEF32483 L22080 AAA35502 L23805 AAA86430 U03100 AAA18949 XM_005271899 XP_005271956 XM_006714536 XP_006714599 XM_011543172 XP_011541474 NM_001290307 NP_001277236 NM_001290309 NP_001277238 NM_001290310 NP_001277239 NM_001290312 NP_001277241 NM_001903 NP_001894
Function	Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.
Subcellular Location	Isoform 1: Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction. Note=Found at cell-cell boundaries and probably at cell-matrix boundaries.
Tissue Specificity	Expressed ubiquitously in normal tissues.
Top Pathways	Adherens junction, Tight junction, Leukocyte transendothelial migration, Endometrial cancer, Arrhythmogenic right ventricular cardiomyopathy (ARVC)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CTNNA1 / Catenin Alpha-1 ELISA Kit (Sandwich ELISA) - LS-F9434 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.054 ng/ml Range 0.156-10 ng/ml

Catenin, Alpha 1, CTNNa1, Human, ELISA Kit - E-EL-H0665 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Enin alpha-1 (CTNNA1), Human, ELISA Kit - E01E0193 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 0.5-10 ng/mL,

Catenin, Alpha 1, CTNNa1, Mouse, ELISA Kit - E-EL-M0247 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Catenin, Alpha 1, CTNNa1, Rat, ELISA Kit - E-EL-R0169 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Catenin, Alpha 1, CTNNa1, Rabbit, ELISA Kit - E-EL-RB0672 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Catenin, Alpha 1, CTNNa1, Chicken, ELISA Kit - E-EL-Ch0553 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Catenin, Alpha 1, CTNNa1, Porcine, ELISA Kit - E-EL-P0934 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Catenin, Alpha 1, CTNNa1, Sheep, ELISA Kit - E-EL-S0638 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Catenin, Alpha 1, CTNNa1, Guinea Pig, ELISA Kit - E-EL-GP0223 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Catenin, Alpha 1, CTNNa1, Monkey, ELISA Kit - E-EL-MK0764 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human CTNNa1 ELISA Kit - HC0593 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine CTNNa1 ELISA Kit - AC0593 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

CTNNa1, ELISA Kit - MBS2513712 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 46.875pg/mL Range 78.125-5000pg/mL

CTNNa1, ELISA Kit - MBS2511819 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

Catenin-alpha1 Colorimetric Cell-Based ELISA Kit - CB5105 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Catenin Alpha 1, ELISA Kit - MBS085767 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Catenin Alpha 1, ELISA Kit - MBS060425 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Catenin Alpha 1, ELISA Kit - MBS088091 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Catenin Alpha 1, ELISA Kit - MBS065830 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Catenin Alpha 1, ELISA Kit - MBS061004 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Catenin Alpha 1, ELISA Kit - MBS083789 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Catenin Alpha 1, ELISA Kit - MBS084305 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Catenin Alpha 1, ELISA Kit - MBS057944 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Catenin Alpha 1, ELISA Kit - MBS088161 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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