GOT1

Gene Symbol	GOT1
Entrez Gene	2805
Alt Symbol	ASTQTL1, GIG18, cAspAT, cCAT
Species	Human
Gene Type	protein-coding
Description	glutamic-oxaloacetic transaminase 1, soluble
Other Description	aspartate aminotransferase 1|aspartate aminotransferase, cytoplasmic|aspartate transaminase 1|cysteine aminotransferase, cytoplasmic|cysteine transaminase, cytoplasmic|glutamate oxaloacetate transaminase 1|growth-inhibiting protein 18|transaminase A
Swissprots	Q5VW80 P17174 B7Z7E9 B2R6R7
Accessions	AAC32851 CBF96059 CBV09579 EAW49868 EAW49869 P17174 AF052153 AAC28622 AK293483 BAH11518 AK301916 BAH13585 AK309174 AK312684 BAG35564 AY513279 AAT08032 BC000498 AAH00498 DA581933 EB387028 M37400 AAA35563 XR_945681 NM_002079 NP_002070
Function	Biosynthesis of L-glutamate from L-aspartate or L- cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3- mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain. {ECO:0000269|PubMed:16039064}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:1974457}.
Top Pathways	Cysteine and methionine metabolism, Alanine, aspartate and glutamate metabolism, Phenylalanine metabolism, Tyrosine metabolism, Biosynthesis of amino acids

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rat Aspartate Aminotransferase ELISA Kit (Sandwich ELISA) - LS-F4448 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.34 ng/ml Range 0.781-50 ng/ml

Mouse Aspartate Aminotransferase ELISA Kit (Sandwich ELISA) - LS-F4449 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.128 ng/ml Range 0.781-50 ng/ml

Human Aspartate Aminotransferase ELISA Kit (Sandwich ELISA) - LS-F4659 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 0.313 ng/ml Range 0.781-50 ng/ml

Bovine Aspartate Aminotransferase ELISA Kit (Sandwich ELISA) - LS-F8421 from LifeSpan Bioscience Category ELISA Kit Prices $820.00 Sizes 1 plate Sensitivity 0.055 ng/ml Range 0.781-50 ng/ml

Rat Aspartate Aminotransferase ELISA Kit (Sandwich ELISA) - LS-F10707 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 3.12 Range 0.781-50 ng/ml

Pig Aspartate Aminotransferase ELISA Kit (Sandwich ELISA) - LS-F10708 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.312 Range 0.781-50 ng/ml

Mouse Aspartate Aminotransferase ELISA Kit (Sandwich ELISA) - LS-F10709 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 1.56 Range 0.781-50 ng/ml

GOT1 (Human) IP-WB Antibody Pair - H00002805-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

GOT1 (Human) Matched Antibody Pair - H00002805-AP21 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) , ELISA Kit - MBS700831 from MyBioSource Category ELISA Kit Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.78 mIU/ml Range 3.12 mIU/ml-200 mIU/ml

ELISA Kit for Aspartate Aminotransferase (AST) - SEB214Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.142ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Aspartate Aminotransferase (AST) - SEB214Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.128ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Aspartate Aminotransferase (AST) - SEB214Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.34ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA’s were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

ELISA Kit for Aspartate Aminotransferase (AST) - SEB214Bo from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.055ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human Aspartate aminotransferase,AST ELISA Kit - CSB-E09603h from Cusabio Category ELISA Kit Sensitivity 0.39 mIU/ml Range 1.56 mU/ml-100 mU/ml

Bovine Aspartate Aminotransferase ELISA Kit (Custom ELISA) - LS-F16454 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.781-50 ng/ml

Chicken Aspartate Aminotransferase ELISA Kit (Custom ELISA) - LS-F16455 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.781-50 ng/ml

Human Aspartate Aminotransferase ELISA Kit (Custom ELISA) - LS-F16456 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.781-50 ng/ml

Rabbit Aspartate Aminotransferase ELISA Kit - LS-F16457 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range To be determined

Mouse Aspartate Aminotransferase ELISA Kit (Sandwich ELISA) - LS-F21310 from LifeSpan Bioscience Category ELISA Kit Prices $590.00 Sizes 1 plate Sensitivity 0.094 ng/ml Range 0.781-50 ng/ml

Human Aspartate Aminotransferase ELISA Kit (Sandwich ELISA) - LS-F21953 from LifeSpan Bioscience Category ELISA Kit Prices $590.00 Sizes 1 plate Sensitivity 0.188 ng/ml Range 0.781-50 ng/ml

Rat Aspartate Aminotransferase ELISA Kit (Sandwich ELISA) - LS-F22283 from LifeSpan Bioscience Category ELISA Kit Prices $590.00 Sizes 1 plate Sensitivity 0.188 ng/ml Range 0.781-50 ng/ml

Mouse Aspartate Aminotransferase ELISA Kit (Competitive EIA) - LS-F28188 from LifeSpan Bioscience Category ELISA Kit Prices $870.00 Sizes 1 plate Sensitivity 0.1 ng/ml Range 0.781-50 ng/ml

Rat Aspartate Aminotransferase ELISA Kit (Competitive EIA) - LS-F27863 from LifeSpan Bioscience Category ELISA Kit Prices $870.00 Sizes 1 plate Sensitivity 1 ng/ml Range 0.781-50 ng/ml

Human Aspartate Aminotransferase ELISA Kit (Competitive EIA) - LS-F28763 from LifeSpan Bioscience Category ELISA Kit Prices $870.00 Sizes 1 plate Sensitivity 0.1 ng/ml Range 0.781-50 ng/ml

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