GOT1

Gene Symbol	GOT1
Entrez Gene	2805
Alt Symbol	ASTQTL1, GIG18, cAspAT, cCAT
Species	Human
Gene Type	protein-coding
Description	glutamic-oxaloacetic transaminase 1, soluble
Other Description	aspartate aminotransferase 1|aspartate aminotransferase, cytoplasmic|aspartate transaminase 1|cysteine aminotransferase, cytoplasmic|cysteine transaminase, cytoplasmic|glutamate oxaloacetate transaminase 1|growth-inhibiting protein 18|transaminase A
Swissprots	Q5VW80 P17174 B7Z7E9 B2R6R7
Accessions	AAC32851 CBF96059 CBV09579 EAW49868 EAW49869 P17174 AF052153 AAC28622 AK293483 BAH11518 AK301916 BAH13585 AK309174 AK312684 BAG35564 AY513279 AAT08032 BC000498 AAH00498 DA581933 EB387028 M37400 AAA35563 XR_945681 NM_002079 NP_002070
Function	Biosynthesis of L-glutamate from L-aspartate or L- cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3- mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain. {ECO:0000269|PubMed:16039064}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:1974457}.
Top Pathways	Cysteine and methionine metabolism, Alanine, aspartate and glutamate metabolism, Phenylalanine metabolism, Tyrosine metabolism, Biosynthesis of amino acids

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Aspartate Aminotransferase full length protein - ab99147 from Abcam Category Protein Prices $188.00, $692.00 Sizes 100 µg, 500 µg Source E. coli Species Human

Human Aspartate Aminotransferase full length protein - ab116689 from Abcam Category Protein Prices $188.00 Sizes 5 µg Source E. coli Species Human

Mouse Aspartate Aminotransferase full length protein - ab201889 from Abcam Category Protein Source E. coli Species Mouse

GOT1-Antibody-C-term-Blocking-Peptide - BP2947b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GOT1-Antibody-N-term-Blocking-Peptide - BP2947a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant human Aspartate aminotransferase, cytoplasmic (OPCA00105) - OPCA00105 from Aviva Systems Biology Category Protein Prices $198.00 Sizes 50 µg Species Human

GOT1 Protein (OPPA02305) - OPPA02305 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human GOT1 protein (His Tag) - orb138939 from Biorbyt Category Protein Prices $323.00, $434.00 Sizes 50 μg, 100 μg Source E. coli Species Human

Human GOT1 protein - orb244242 from Biorbyt Category Protein Prices $315.00, $502.00, $782.00, $1,139.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human GOT1 protein - orb49408 from Biorbyt Category Protein Prices $323.00, $485.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

GOT1 protein (His tag) - 80R-1363 from Fitzgerald Category Protein Prices $220.00 Sizes 100 µg Source E.coli

Human AST Protein - abx065466 from Abbexa Category Protein Source E.coli Species Human

Aspartate Aminotransferase Peptide - AC21-1343-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Aspartate Aminotransferase Peptide - AC21-1379-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

GOT1 (1-413, His-tag) - AR09537PU-L from Acris Antibodies Category Protein Prices $695.00 Sizes 500 µg Source E. coli Species Human

GOT1 (1-413, His-tag) - AR09537PU-N from Acris Antibodies Category Protein Prices $305.00 Sizes 100 µg Source E. coli Species Human

GOT1 - H00002805-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

GOT1 - H00002805-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Aspartate Aminotransferase (AST), Human - 20-7543 from ARP American Research Products Category Protein Prices $489.00 Sizes 50 µg Source E.coli Species Human

Glutamate Oxaloacetate Transaminase 1, GOT1, Human, Recombinant - 19-C145 from ARP American Research Products Category Protein Prices $119.00 Sizes 10 µg Source E. coli Species Human

GOT1, 1-413aa, Human, His tag, E.coli - 01-1860-1 from ARP American Research Products Category Protein Prices $159.00, $339.00, $749.00 Sizes 20 µg, 100 µg, 500 µg Species Human

GOT1 Peptide - 45-689P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

GOT1 Peptide - 45-690P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

GOT1 fusion protein - Ag7012 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

GOT1 fusion protein - Ag6671 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

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