EPHA1

Gene Symbol	EPHA1
Entrez Gene	2041
Alt Symbol	EPH, EPHT, EPHT1
Species	Human
Gene Type	protein-coding
Description	EPH receptor A1
Other Description	eph tyrosine kinase 1|ephrin type-A receptor 1|erythropoietin-producing hepatoma amplified sequence|erythropoietin-producing hepatoma receptor|hEpha1|oncogene EPH|soluble EPHA1 variant 1|soluble EPHA1 variant 2|tyrosine-protein kinase receptor EPH
Swissprots	Q15405 B5A966 B5A967 A1L3V3 P21709
Accessions	AAD43440 AAS07458 CCQ43308 EAL23789 EAW51845 EAW51846 EAW51847 P21709 AA723562 AA723620 AA788809 AI057542 AK290351 BAF83040 AK313263 AU131228 BC130291 AAI30292 BC144156 CD653381 CN289899 CN289901 EU826604 ACF47640 EU826605 ACF47641 M18391 AAA36747 Z27409 CAA81796 XM_006715880 XP_006715943 XM_011515878 XP_011514180 XR_428169 NM_005232 NP_005223
Function	Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC. Plays also a role in angiogenesis and regulates cell proliferation. May play a role in apoptosis. {ECO:0000269|PubMed:17634955, ECO:0000269|PubMed:19118217, ECO:0000269|PubMed:20043122}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:19118217}; Single-pass type I membrane protein {ECO:0000269|PubMed:19118217}.
Tissue Specificity	Overexpressed in several carcinomas.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

EphA1 (G-18) - sc-925 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

EphA1 (A-16) - sc-31259 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

EphA1 (D-17) - sc-31257 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

EphA1 (5D2A4) - sc-65993 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

EphA1 (H-120) - sc-20738 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

EphA1 (5D2A10) - sc-65994 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Anti-Eph receptor A1 antibody - ab5376 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-Eph receptor A1 antibody - ab65074 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Eph receptor A1 antibody - ab152145 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-Eph receptor A1 antibody - ab7036 from Abcam Prices $406.00 Sizes 50 µg Host Goat Clonality Polyclonal

Anti-Eph receptor A1 antibody [MM0260- 8D36] - ab89471 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone MM0260- 8D36

Anti-Eph receptor A1 antibody - C-terminal - ab150478 from Abcam Prices $407.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-Eph receptor A1 antibody - Carboxyterminal end - ab37857 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-EPHA1 / EPH Receptor A1 Antibody (aa963-976) - LS-C312729 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-EPHA1 / EPH Receptor A1 Antibody - LS-C117279 from LifeSpan Bioscience Prices $635.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-EPHA1 / EPH Receptor A1 Antibody (Phe568) - LS-C191944 from LifeSpan Bioscience Prices $345.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-EPHA1 / EPH Receptor A1 Antibody (aa338-366, AP) - LS-C222424 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EPHA1 / EPH Receptor A1 Antibody (aa338-366, Biotin) - LS-C222426 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EPHA1 / EPH Receptor A1 Antibody (clone GF1) - LS-C190282 from LifeSpan Bioscience Prices $445.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone GF1

Anti-EPHA1 / EPH Receptor A1 Antibody (aa338-366, FITC) - LS-C222428 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EPHA1 / EPH Receptor A1 Antibody (aa338-366, APC) - LS-C222425 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EPHA1 / EPH Receptor A1 Antibody (aa338-366, Azide-free, HRP) - LS-C222429 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EPHA1 / EPH Receptor A1 Antibody (aa338-366, PE) - LS-C222430 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EPHA1 / EPH Receptor A1 Antibody (aa37-67, AP) - LS-C222431 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EPHA1 / EPH Receptor A1 Antibody (aa37-67, APC) - LS-C222432 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

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