DSC2

Gene Symbol	DSC2
Entrez Gene	1824
Alt Symbol	ARVD11, CDHF2, DG2, DGII/III, DSC3
Species	Human
Gene Type	protein-coding
Description	desmocollin 2
Other Description	cadherin family member 2|desmocollin-2|desmosomal glycoprotein II/III
Swissprots	Q02487
Accessions	ABM88172 CAL91822 CAL91823 EAX01250 EAX01251 Q02487 AK290313 BAF83002 AK297029 BAG59557 BC063291 AAH63291 BE350090 BE813598 BU735677 BX648425 CAH56152 CR749226 CAH18082 DC382631 EF017811 ABM88170 EF017812 ABM88171 X56807 CAA40141 XM_005258206 XP_005258263 NM_004949 NP_004940 NM_024422 NP_077740
Function	Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:21062920}; Single-pass type I membrane protein {ECO:0000269|PubMed:21062920}. Cell junction, desmosome {ECO:0000269|PubMed:21062920}.
Tissue Specificity	Expressed in epithelia, myocardium and lymph nodes.
Top Pathways	Arrhythmogenic right ventricular cardiomyopathy (ARVC)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DSC2 / Desmocollin 2 ELISA Kit (Sandwich ELISA) - LS-F8108 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.107 ng/ml Range 0.313-20 ng/ml

Human Desmocollin 2 ELISA Kit - abx151298 from Abbexa Category ELISA Kit Sensitivity 0.107 ng/ml Range 0.313 ng/ml - 20 ng/ml

Desmocollin 2 (DSC2), Human, ELISA Kit - SEG436Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.107ng/mL Range 0.312-20ng/mL

Desmocollin-2/desmosomal glycoprotein II (DSC2), Human, ELISA Kit - CSB-E13914h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

DSC2 (Human) IP-WB Antibody Pair - H00001824-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

DSC2 (Human) Matched Antibody Pair - H00001824-AP51 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Desmocollin 2, ELISA Kit - MBS098357 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Desmocollin 2, ELISA Kit - MBS085418 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Desmocollin 2, ELISA Kit - MBS100010 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Desmocollin 2, ELISA Kit - MBS097720 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Desmocollin 2, ELISA Kit - MBS058818 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Desmocollin 2, ELISA Kit - MBS062182 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

desmocollin 2, ELISA Kit - MBS704249 from MyBioSource Category ELISA Kit Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Desmocollin 2, ELISA Kit - MBS073471 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Desmocollin 2 (DSC2), ELISA Kit - MBS2023194 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human DSC2 is typically less than 0.107ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.312-20ng/mL

ELISA Kit for Desmocollin 2 (DSC2) - SEG436Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.107ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human desmocollin-2/desmosomal glycoprotein II (DSC2) ELISA Kit - CSB-E13914h from Cusabio Category ELISA Kit Sensitivity Request Information Range Request Information

ELISA Kit for Desmocollin 2 (DSC2) - SEG436Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.107ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Custom Human Desmocollin-2 ELISA - ELH-DSC2 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human Desmocollin 2 (DSC2) ELISA Kit - EKU03706 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.107 ng/mL Range 0.312-20 ng/mL

Human Desmocollin-2 ELISA - RAB1422 from Sigma-Aldrich Prices $615.00 Sizes 1 kt

Human desmocollin-2/desmosomal glycoprotein II (DSC2) ELISA Kit - EKC33443 from Biomatik Category ELISA Kit Prices $795.00, $3,021.00, $5,645.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.04 ng/ml Range 10 ng/ml-0.16 ng/ml

Custom Human Desmocollin-2 ELISA - ELH-DSC2-1 from RayBiotech Category ELISA Kit Prices $627.00, $1,128.60, $2,508.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

DSC2 ELISA Kit (Human) (OKCD00997) - OKCD00997 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.107 ng/mL Range 0.312-20 ng/mL

Desmocollin 2 (DSC2), ELISA Kit - MBS451966 from MyBioSource Category ELISA Kit Prices $415.00, $550.00, $2,425.00, $4,710.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.107ng/mL Range 0.312-20ng/mL

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