DSC2

Gene Symbol DSC2
Entrez Gene 1824
Alt Symbol ARVD11, CDHF2, DG2, DGII/III, DSC3
Species Human
Gene Type protein-coding
Description desmocollin 2
Other Description cadherin family member 2|desmocollin-2|desmosomal glycoprotein II/III
Swissprots Q02487
Accessions ABM88172 CAL91822 CAL91823 EAX01250 EAX01251 Q02487 AK290313 BAF83002 AK297029 BAG59557 BC063291 AAH63291 BE350090 BE813598 BU735677 BX648425 CAH56152 CR749226 CAH18082 DC382631 EF017811 ABM88170 EF017812 ABM88171 X56807 CAA40141 XM_005258206 XP_005258263 NM_004949 NP_004940 NM_024422 NP_077740
Function Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.
Subcellular Location Cell membrane {ECO:0000269|PubMed:21062920}; Single-pass type I membrane protein {ECO:0000269|PubMed:21062920}. Cell junction, desmosome {ECO:0000269|PubMed:21062920}.
Tissue Specificity Expressed in epithelia, myocardium and lymph nodes.
Top Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Human Desmocollin 2 full length protein - ab158317 from Abcam

Category Protein
Source Wheat germ
Species Human
ab158317 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human Desmocollin 2 protein fragment - ab158318 from Abcam

Category Protein
Source Wheat germ
Species Human
ab158318 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human Desmocollin 2 protein fragment - ab158319 from Abcam

Category Protein
Source Wheat germ
Species Human
ab158319 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human Desmocollin 2 protein fragment - ab190408 from Abcam

Category Protein
Source E. coli
Species Human

Recombinant Human Desmocollin-2, CF - 4688-DC-050 from R&D Systems

Category Protein
Source Mouse myeloma cell line, NS0-derived, Arg136-Arg684, with a C-terminal 6-His tag

Desmocollin-2 - H00001824-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

Desmocollin-2 - H00001824-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

Desmocollin-2 - H00001824-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

Desmocollin-2 - H00001824-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

Desmocollin-2 - H00001824-Q02 from Acris Antibodies

Category Protein
Prices $370.00
Sizes 10 µg
Species Human

Desmocollin-2 - H00001824-Q02-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

Desmocollin-2 - H00001824-Q02-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

DSC2 fusion protein - ag4956 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

DSC2 fusion protein - Ag5450 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

Recombinant Human DSC2, His tagged - DSC2-3856H from Creative Biomart

Category Protein
Source Human Cells
Species Human

DSC2 - PN201490 from Elabscience

Category Protein
Prices $225.00, $475.00
Sizes 10 μg, 50 μg
Source Human Cells
Species Human

Recombinant Desmocollin 2 (DSC2) - RPG436Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Human DSC2 / Desmocollin-2 Protein (His Tag) - 10809-H08H-50 from Sino Biological

Category Protein
Source Human Cells
Species Human

Recombinant Desmocollin 2 (DSC2) - RPG436Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human

Recombinant Human Desmocollin-2 Protein, CF - 4688-DC from R&D Systems

Category Protein
Prices $329.00
Sizes 50 µg
Source Mouse myeloma cell line, NS0-derived Arg136-Arg684, with a C-terminal 6-His tag
Species Human

Desmocollin 2 Protein (Recombinant) - abx168158 from Abbexa

Category Protein
Source Human
Species Human

Desmocollin-2 (transcript variant Dsc2a) - TP309218 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
Desmocollin-2

Desmocollin-2 (transcript variant Dsc2b) - TP322207 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
Desmocollin-2

Recombinant Human DSC2 / Desmocollin-2 Protein (His tag) - PKSH031417 from Elabscience

Category Protein
Source Human Cell
Species Human

Recombinant Desmocollin 2 (DSC2) - RPU52298 from Biomatik

Category Protein
Prices $185.00, $378.00, $578.00, $688.80
Sizes 10 µg, 50 µg, 100 µg, 200 µg
Source E.coli
Species Human
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