DSC2

Gene Symbol DSC2
Entrez Gene 1824
Alt Symbol ARVD11, CDHF2, DG2, DGII/III, DSC3
Species Human
Gene Type protein-coding
Description desmocollin 2
Other Description cadherin family member 2|desmocollin-2|desmosomal glycoprotein II/III
Swissprots Q02487
Accessions ABM88172 CAL91822 CAL91823 EAX01250 EAX01251 Q02487 AK290313 BAF83002 AK297029 BAG59557 BC063291 AAH63291 BE350090 BE813598 BU735677 BX648425 CAH56152 CR749226 CAH18082 DC382631 EF017811 ABM88170 EF017812 ABM88171 X56807 CAA40141 XM_005258206 XP_005258263 NM_004949 NP_004940 NM_024422 NP_077740
Function Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.
Subcellular Location Cell membrane {ECO:0000269|PubMed:21062920}; Single-pass type I membrane protein {ECO:0000269|PubMed:21062920}. Cell junction, desmosome {ECO:0000269|PubMed:21062920}.
Tissue Specificity Expressed in epithelia, myocardium and lymph nodes.
Top Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC)

DSC2 CRISPR/Cas9 KO Plasmid (h) - sc-403386 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DSC2 HDR Plasmid (h) - sc-403386-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DSC2 Double Nickase Plasmid (h) - sc-403386-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DSC2 Double Nickase Plasmid (h2) - sc-403386-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DSC2 CRISPR Activation Plasmid (h) - sc-403386-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DSC2 CRISPR Activation Plasmid (h2) - sc-403386-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DSC2 Lentiviral Activation Particles (h) - sc-403386-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DSC2 Lentiviral Activation Particles (h2) - sc-403386-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DSC2 siRNA (h) - sc-45373 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DSC2 shRNA Plasmid (h) - sc-45373-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DSC2 shRNA (h) Lentiviral Particles - sc-45373-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU157951 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7496 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7496 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

DSC2 siRNA (Human) - CRH1273 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Desmocollin-2 RNAi - H00001824-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

DSC2 - MBS8223218 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Dsc2 (NM_004949.3) - SHH281129 from Creative biogene

Category siRNA
Species Reactivities Human

Human DSC2 siRNA - orb261775 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DSC2 shRNA Plasmid (Human) - CHH1273 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DSC2 miRNA 3'UTR clone - MiUTR4H-TG02872 from Creative biogene

Species Reactivities Human
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