ADCY1

Gene Symbol ADCY1
Entrez Gene 107
Alt Symbol AC1, DFNB44
Species Human
Gene Type protein-coding
Description adenylate cyclase 1 (brain)
Other Description 3',5'-cyclic AMP synthetase|ATP pyrophosphate-lyase 1|Ca(2+)/calmodulin-activated adenylyl cyclase|adenyl cyclase|adenylate cyclase type 1|adenylate cyclase type I|adenylyl cyclase 1
Swissprots Q08828 Q75MI1 A4D2L8
Accessions AAS07467 CAD99233 EAL23741 EAW61042 EAW61043 EAW61044 EAW61045 EAW61046 EAW61047 Q08828 AB209496 BAD92733 AF086306 AF497515 AAM94372 AK024415 AK055343 AK095518 AK095665 AL707720 AW956248 BC036858 BC041473 BC169213 BC169214 BU181704 L05500 AAA02907 XM_005249584 XP_005249641 XM_005249585 XP_005249642 NM_001281768 NP_001268697 NM_021116 NP_066939
Function This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina (By similarity). {ECO:0000250}.
Subcellular Location Membrane; Multi-pass membrane protein. Cytoplasm {ECO:0000250|UniProtKB:O88444}. Note=Expressed in the cytoplasm of supporting cells and hair cells of the cochlea vestibule, as well as to the cochlear hair cell nuclei and stereocilia. {ECO:0000250|UniProtKB:O88444}.
Tissue Specificity Brain, retina and adrenal medulla.
Top Pathways Oxytocin signaling pathway, Adrenergic signaling in cardiomyocytes, Inflammatory mediator regulation of TRP channels, Calcium signaling pathway, Gap junction

A cyclase (C-5) - sc-377243 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
A cyclase (C-5): sc-377243. Western blot analysis of A cyclase expression in rat heart (A), human heart (B) and human ovary (C) tissue extracts and IMR-32 (D) whole cell lysate.

A cyclase (R-32) - sc-1701 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
A cyclase (R-32): sc-1701. Western blot analysis of insect cells transfected with an A cyclase IV baculovirus expression vector.

A cyclase I (F-10) - sc-365350 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
A cyclase I (F-10): sc-365350. Western blot analysis of A cyclase I expression in ARPE-19 whole cell lysate.

A cyclase I (V-20) - sc-586 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
A cyclase I (V-20): sc-586. Western blot analysis of A cyclase I expression in Y79 (A), ARPE-19 (B) and IMR-32 (C) whole cell lysates.

A cyclase I (H-70) - sc-25743 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
A cyclase I (H-70): sc-25743. Immunoperoxidase staining of formalin fixed, paraffin-embedded human bronchus tissue showing nuclear and cytoplasmic staining of respiratory epithelial cells.

Anti-ADCY1 / Adenylate Cyclase 1 Antibody (Asp252) - LS-C176963 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
IHC of A Cyclase I (D252) pAb in paraffin-embedded human brain tissue.

Anti-ADCY1 / Adenylate Cyclase 1 Antibody (aa303-569) - LS-C314759 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant ADCY1 / Adenylate Cyclase 1.

Anti-ADCY1 / Adenylate Cyclase 1 Antibody (aa835-1061) - LS-C314758 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant ADCY1 / Adenylate Cyclase 1.

Anti-ADCY1 / Adenylate Cyclase 1 Antibody (aa231-280) IHC-plus™ - LS-B10007 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Huma Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

Adenylate Cyclase 1 Antibody - NBP1-19628 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Adenylate Cyclase 1 Antibody [NBP1-19628] - Lane1:Hela whole cell lysate. Lane2:HEK293T whole cell lysate. Lane3:Mouse liver tissue lysate. Lane4:Rat kidney tissue lysate.

Adenylate Cyclase 1 Antibody - NBP1-66411 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Adenylate Cyclase 1 Antibody [NBP1-66411] - Analysis of extracts from COLO205 cells, using Adenylate Cyclase 1 Antibody. The lane on the right is treated with the synthesized peptide.

ADCY1 Polyclonal Antibody - bs-3681R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat brain labeled with Anti-ADCY1 Polyclonal Antibody, Unconjugated (bs-3681R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

Anti-ADCY1 antibody produced in rabbit - SAB4500146 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ADCY1: <B>Cat. No. SAB4500146</B>: Immunoblotting analysis of extracts from COLO205 cells, using Anti-ADCY1 antibody. The lane on the left was treated with the Anti-ADCY1 antibody. The lane on the right (negative control) was treated with both Anti-ADCY1 antibody and the synthesized immunogen peptide.

Anti-ADCY1 antibody produced in rabbit - SAB4301056 from Sigma-Aldrich

Prices $230.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ADCY1 antibody produced in rabbit - SAB4300903 from Sigma-Aldrich

Prices $230.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ADCY1: <B>Cat. No. SAB4300903</B>: Western blot analysis of extracts from COLO205 cells using Anti-ADCY1 antibody.

ADCY1 Antibody (OAAF02812) - OAAF02812 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

ADCY1 antibody - orb67118 from Biorbyt

Prices $476.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal
Western blot of total cell extracts from mouse brain using ADCY1 antibody

ADCY1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-3681R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ADCY1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-3681R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ADCY1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-3681R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ADCY1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-3681R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ADCY1 Polyclonal Antibody, Cy3 Conjugated - bs-3681R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ADCY1 Polyclonal Antibody, Cy5 Conjugated - bs-3681R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ADCY1 Polyclonal Antibody, Cy5.5 Conjugated - bs-3681R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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