DVL1

Gene Symbol	DVL1
Entrez Gene	1855
Alt Symbol	DVL, DVL1L1, DVL1P1
Species	Human
Gene Type	protein-coding
Description	dishevelled segment polarity protein 1
Other Description	DSH homolog 1|dishevelled 1 (homologous to Drosophila dsh)|dishevelled, dsh homolog 1|dishevelled-1|segment polarity protein dishevelled homolog DVL-1
Swissprots	O14640 Q5TA35 Q5TA33
Accessions	EAW56224 EAW56225 EAW56226 EAW56227 O14640 P54792 AB209210 BAD92447 AF006011 AAB65242 AK093189 BAC04089 AK095867 BAG53150 AK293286 BAH11484 AK300063 BAH13201 BC017225 AAH17225 BC025292 BC050454 AAH50454 BC111419 BP305846 U46461 AAC50682 XM_005244731 XP_005244788 XM_005244732 XP_005244789 XM_005244733 XP_005244790 NM_004421 NP_004412 NM_181870 NM_182779
Function	Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ).
Subcellular Location	Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Note=Localizes at the cell membrane upon interaction with frizzled family members. {ECO:0000250}.
Top Pathways	Wnt signaling pathway, Notch signaling pathway, Basal cell carcinoma, Melanogenesis, HTLV-I infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Dishevelled / Dvl1 protein fragment - ab116823 from Abcam Category Protein Source Wheat germ Species Human

DVL1-Antibody-Center-Blocking-peptide - BP12326c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DVL1 Protein Lysate (APL11069) - APL11069 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

DVL1 Protein Lysate (APL11070) - APL11070 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

Human DVL1 Protein - abx066348 from Abbexa Category Protein Source E.coli Species Human

Dishevelled-1 / DVL1 - H00001855-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

Dishevelled-1 / DVL1 - H00001855-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Dishevelled-1 / DVL1 - H00001855-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DVL1 fusion protein - ag5718 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

DVL1 fusion protein - ag5550 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human DVL1 - DVL1-28351TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Dishevelled, Dsh Homolog 1 (DVL1) - RPJ540Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Dishevelled, Dsh Homolog 1 (DVL1) - RPJ540Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Dishevelled, Dsh Homolog 1 (DVL1) - RPJ540Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Segment polarity protein dishevelled homolog DVL-1(DVL1) - CSB-YP007284HU CSB-EP007284HU CSB-BP007284HU CSB-MP007284HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Segment polarity protein dishevelled homolog DVL-1-like(DVL1L1 - CSB-YP007285HU CSB-EP007285HU CSB-BP007285HU CSB-MP007285HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Dishevelled, Dsh Homolog 1 (DVL1) - RPU141210 from Biomatik Category Protein Prices $231.00, $462.00, $693.00 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Human

DVL1L1-Blocking-Peptide-N-Term - BP21836a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DVL1 Protein Lysate - orb333643 from Biorbyt Category Protein Prices $400.00 Sizes 200 μg Species Human

DVL1 Protein Lysate - orb333642 from Biorbyt Category Protein Prices $400.00 Sizes 200 μg Species Human

Recombinant Dishevelled, Dsh Homolog 1 (DVL1) - RPU41210 from Biomatik Category Protein Prices $185.00, $378.00, $578.00, $688.80 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

DVL1 Recombinant Protein (OPCD02820) - OPCD02820 from Aviva Systems Biology Category Protein Source E.coli Species Human

Dishevelled, Dsh Homolog 1 (DVL1), Recombinant Protein - MBS2018278 from MyBioSource Category Protein Prices $185.00, $380.00, $585.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

Segment polarity protein dishevelled homolog DVL-1 (DVL1), Recombinant Protein - MBS1024037 from MyBioSource Category Protein Prices $1,500.00, $1,500.00, $1,730.00, $1,730.00, $2,565.00, $2,565.00, $3,010.00, $3,010.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Segment polarity protein dishevelled homolog DVL-1-like (DVL1L1), Recombinant Protein - MBS951050 from MyBioSource Category Protein Prices $1,470.00, $1,470.00, $1,700.00, $1,700.00, $2,510.00, $2,510.00, $2,950.00, $2,950.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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