Foxo3

Gene Symbol	Foxo3
Entrez Gene	56484
Alt Symbol	1110048B16Rik, 2010203A17Rik, C76856, FKHRL1, Fkhr2, Foxo3a
Species	Mouse
Gene Type	protein-coding
Description	forkhead box O3
Other Description	forkhead box O3a|forkhead box protein O3|forkhead protein FKHR2
Swissprots	Q05CZ4 D3Z6Y6 Q9WVH4
Accessions	EDL04998 Q9WVH4 AF114259 AAD42107 AK004198 AK008417 AK041595 BAE20596 AK047413 BAC33049 AK047922 AK079567 AK139629 AK143198 AK159465 BAE35106 BC019532 AAH19532 BC050975 BC100372 BC166015 AAI66015 XM_006512806 XP_006512869 NM_019740 NP_062714
Function	Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post- transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm, cytosol {ECO:0000250}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00089}. Note=Translocates to the nucleus upon oxidative stress and in the absence of survival factors. {ECO:0000250}.
Tissue Specificity	Expressed in white and brown adipose tissues (at protein level). {ECO:0000269|PubMed:22510882}.
Top Pathways	Non-small cell lung cancer, Endometrial cancer, Neurotrophin signaling pathway, Chemokine signaling pathway, PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Forkhead Box Protein O3 (FOXO3), Mouse, ELISA Kit - SEA762Mu from ARP American Research Products Category ELISA Kit Prices $668.00 Sizes 96 t Sensitivity 0.054ng/mL Range 0.156-10ng/mL

Mouse FOXO3 ELISA Kit - MF0124 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Mouse Forkhead Box Protein O3 ELISA - E03F0117 from BlueGene Biotech Category ELISA Kit Sensitivity 0.1 ng/mL

ELISA Kit for Forkhead Box Protein O3 (FOXO3) - SEA762Mu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.054ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Mouse FOXO3 ELISA Kit - abx154035 from Abbexa Category ELISA Kit Sensitivity 0.054 ng/ml Range 0.156 ng/ml - 10 ng/ml

Forkhead Box Protein O3 (FOXO3), Mouse, ELISA Kit - DL-FOXO3-Mu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Range 0.156-10 ng/mL

Mouse FOXO3 ELISA Kit - abx571029 from Abbexa Category ELISA Kit Sensitivity 0.054 ng/ml Range 0.156 ng/ml - 10 ng/ml

Mouse FOXO3A ELISA Kit - E053333 from Biobool Category ELISA Kit

Mouse Foxo3 ELISA Kit - E053358 from Biobool Category ELISA Kit

FOXO3 ELISA Kit (Mouse) (OKDD00710) - OKDD00710 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity <0.054 ng/mL Range 0.156-10 ng/mL

Mouse FOXO3 ELISA Kit - EMF0124 from ABclonal Category ELISA Kit Prices $495.00 Sizes 96 t

Forkhead Box Protein O3 (FOXO3), ELISA Kit - MBS450044 from MyBioSource Category ELISA Kit Prices $395.00, $520.00, $2,275.00, $4,420.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.054ng/mL Range 0.156-10ng/mL

FOXO3 (Forkhead box protein O3), ELISA Kit - MBS7606118 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/ml Range 0.156-10ng/ml

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