Foxo3

Gene Symbol Foxo3
Entrez Gene 56484
Alt Symbol 1110048B16Rik, 2010203A17Rik, C76856, FKHRL1, Fkhr2, Foxo3a
Species Mouse
Gene Type protein-coding
Description forkhead box O3
Other Description forkhead box O3a|forkhead box protein O3|forkhead protein FKHR2
Swissprots Q05CZ4 D3Z6Y6 Q9WVH4
Accessions EDL04998 Q9WVH4 AF114259 AAD42107 AK004198 AK008417 AK041595 BAE20596 AK047413 BAC33049 AK047922 AK079567 AK139629 AK143198 AK159465 BAE35106 BC019532 AAH19532 BC050975 BC100372 BC166015 AAI66015 XM_006512806 XP_006512869 NM_019740 NP_062714
Function Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post- transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, cytosol {ECO:0000250}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00089}. Note=Translocates to the nucleus upon oxidative stress and in the absence of survival factors. {ECO:0000250}.
Tissue Specificity Expressed in white and brown adipose tissues (at protein level). {ECO:0000269|PubMed:22510882}.
Top Pathways Non-small cell lung cancer, Endometrial cancer, Neurotrophin signaling pathway, Chemokine signaling pathway, PI3K-Akt signaling pathway

Recombinant Forkhead Box Protein O3 (FOXO3) - RPA762Mu01 from Cloud-clone

Category Protein
Source E.coli
Species Mouse

Recombinant Forkhead Box Protein O3 (FOXO3) - RPA762Mu02 from Cloud-clone

Category Protein
Source E.coli
Species Mouse

Recombinant Mouse Forkhead box protein O3(Foxo3) - CSB-YP895304MO CSB-EP895304MO CSB-BP895304MO CSB-MP895304MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

FOXO3 Protein - abx163265 from Abbexa

Category Protein
Species Human, Mouse

Recombinant Mouse FOXO3 Protein - FOXO3-6007M from Creative Biomart

Category Protein
Source Mammalian Cells
Species Mouse

Forkhead box protein O3 (Foxo3), Recombinant Protein - MBS1403260 from MyBioSource

Category Protein
Prices $1,475.00, $1,475.00, $1,700.00, $1,700.00, $2,510.00, $2,510.00, $2,950.00, $2,950.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse
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