GOSR1

Gene Symbol GOSR1
Entrez Gene 9527
Alt Symbol GOLIM2, GOS-28, GOS28, GOS28/P28, GS28, P28
Species Human
Gene Type protein-coding
Description golgi SNAP receptor complex member 1
Other Description 28 kDa Golgi SNARE protein|28 kDa cis-Golgi SNARE p28|Golgi SNAP receptor complex member 1|Golgi SNARE 28 kDa|cis-golgi SNARE|golgi integral membrane protein 2
Swissprots O95249 J3KST5 O75392
Accessions AAK01856 EAW51229 EAW51230 EAW51231 O95249 AF047438 AAC39889 AF073926 AAD12945 AK000606 AK074298 AK128816 AK291381 BAF84070 AK298714 BAG60870 AL049346 BC012620 AAH12620 BC040072 BC040471 AAH40471 BE785872 BG654545 CB054624 XM_005258070 XP_005258127 XM_005258071 XP_005258128 XM_005258072 XP_005258129 NM_001007024 NP_001007025 NM_001007025 NP_001007026 NM_004871 NP_004862
Function Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide- sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi. {ECO:0000269|PubMed:15215310, ECO:0000269|PubMed:21860593}.
Subcellular Location Golgi apparatus membrane {ECO:0000269|PubMed:15215310, ECO:0000269|PubMed:15728195, ECO:0000269|PubMed:17274796, ECO:0000269|PubMed:17337506, ECO:0000269|PubMed:21669198}; Single-pass type IV membrane protein {ECO:0000269|PubMed:15215310, ECO:0000269|PubMed:15728195, ECO:0000269|PubMed:17274796, ECO:0000269|PubMed:17337506, ECO:0000269|PubMed:21669198}. Note=Localizes throughout the Golgi apparatus, with lowest levels in the trans-Golgi network (By similarity). Enriched on vesicular components at the terminal rims of the Golgi. Found in Golgi microtubules at low temperature (15 degrees Celsius). {ECO:0000250}.
Top Pathways SNARE interactions in vesicular transport

GS28 (F-11) - sc-271551 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GS28 (F-11): sc-271551. Immunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing cytoplasmic staining of glandular cells.

GS28 (E-7) - sc-133148 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GS28 (E-7): sc-133148. Western blot analysis of GS28 expression in JAR (A) and WEHI-231 (B) whole cell lysates.

GS28 (FL-250) - sc-30096 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
GS28 (FL-250): sc-30096. Western blot analysis of GS28 expression in WEHI-231 (A) and MIA PaCa-2 (B) whole cell lysates.

GS28 (L-15) - sc-15271 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GS28 (L-15): sc-15271. Western blot analysis of GS28 expression in WEHI-231 whole cell lysate.

GS28 (N-16) - sc-15270 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GS28 (N-16): sc-15270. Western blot analysis of GS28 expression in WEHI-231 (A) and JAR (B) whole cell lysates.

GS28 (1) - sc-135933 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
GS28 (1): sc-135933. Western blot analysis of GS28 expression in RSV-3T3 whole cell lysate.

Anti-GOSR1 antibody - ab88462 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-GOSR1 antibody (ab88462) at 5 µg/ml + Human liver lysate at 25 µgSecondaryGoat Anti-Mouse IgG at 1/2500 dilution

Anti-GOSR1 antibody [EP1768Y] - ab53288 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1768Y
All lanes : Anti-GOSR1 antibody [EP1768Y] (ab53288) at 1/500 dilutionLane 1 : SKBR-3 cell lysateLane 2 : 3T3 cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-GS28 / GOSR1 / p28 Antibody - LS-C15627 from LifeSpan Bioscience

Prices $375.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-GS28 / GOSR1 / p28 Antibody (aa2-100) - LS-C307733 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-GS28 / GOSR1 / p28 Antibody - LS-C307734 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-GS28 / GOSR1 / p28 Antibody - LS-C311181 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GS28 / GOSR1 / p28 Antibody (C-Terminus) - LS-C135541 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GOSR1 antibody LS-C135541 Western blot of Fetal Liver lysate.

Anti-GS28 / GOSR1 / p28 Antibody (clone HFD9) - LS-C63297 from LifeSpan Bioscience

Prices $325.00, $510.00
Sizes 50 µg, 200 µg
Host Mouse
Clonality Monoclonal
Clone HFD9

Anti-GS28 / GOSR1 / p28 Antibody (aa11-60) IHC-plus™ - LS-B11370 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-GS28 / GOSR1 / p28 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11370 concentration 20 ug/ml.

Anti-GS28 / GOSR1 / p28 Antibody (N-Terminus, clone EP1768Y) - LS-C50039 from LifeSpan Bioscience

Prices $450.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1768Y
IHC of paraffin-embedded human stomach carcinoma using anti-GOS-28 antibody.

GOSR1 Antibody - H00009527-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

GOSR1 Antibody (EP1768Y) - NB100-79960 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1768Y
Western Blot: GOSR1 Antibody (EP1768Y) [NB100-79960] - (A) SKBR-3 cell lysate and (B) 3T3 cell lysate using a 1:500 dilution.

GOSR1 Antibody - H00009527-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: GOSR1 Antibody [H00009527-B01] - GOSR1 MaxPab polyclonal antibody (B01), Lot # 08067 WULz. Western Blot analysis of GOSR1 expression in human liver.

GOSR1 Antibody - NBP1-83351 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GOSR1 Antibody (2C2) - H00009527-M13 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2C2

GOSR1 Antibody - H00009527-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GOSR1/GS28 Polyclonal Antibody - bs-13493R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GOSR1/GS28 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13493R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GOSR1/GS28 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13493R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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