GOSR1

Gene Symbol GOSR1
Entrez Gene 9527
Alt Symbol GOLIM2, GOS-28, GOS28, GOS28/P28, GS28, P28
Species Human
Gene Type protein-coding
Description golgi SNAP receptor complex member 1
Other Description 28 kDa Golgi SNARE protein|28 kDa cis-Golgi SNARE p28|Golgi SNAP receptor complex member 1|Golgi SNARE 28 kDa|cis-golgi SNARE|golgi integral membrane protein 2
Swissprots O95249 J3KST5 O75392
Accessions AAK01856 EAW51229 EAW51230 EAW51231 O95249 AF047438 AAC39889 AF073926 AAD12945 AK000606 AK074298 AK128816 AK291381 BAF84070 AK298714 BAG60870 AL049346 BC012620 AAH12620 BC040072 BC040471 AAH40471 BE785872 BG654545 CB054624 XM_005258070 XP_005258127 XM_005258071 XP_005258128 XM_005258072 XP_005258129 NM_001007024 NP_001007025 NM_001007025 NP_001007026 NM_004871 NP_004862
Function Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide- sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi. {ECO:0000269|PubMed:15215310, ECO:0000269|PubMed:21860593}.
Subcellular Location Golgi apparatus membrane {ECO:0000269|PubMed:15215310, ECO:0000269|PubMed:15728195, ECO:0000269|PubMed:17274796, ECO:0000269|PubMed:17337506, ECO:0000269|PubMed:21669198}; Single-pass type IV membrane protein {ECO:0000269|PubMed:15215310, ECO:0000269|PubMed:15728195, ECO:0000269|PubMed:17274796, ECO:0000269|PubMed:17337506, ECO:0000269|PubMed:21669198}. Note=Localizes throughout the Golgi apparatus, with lowest levels in the trans-Golgi network (By similarity). Enriched on vesicular components at the terminal rims of the Golgi. Found in Golgi microtubules at low temperature (15 degrees Celsius). {ECO:0000250}.
Top Pathways SNARE interactions in vesicular transport

Human GOSR1 full length protein - ab160530 from Abcam

Category Protein
Source Wheat germ
Species Human
ab160530 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human GOSR1 protein fragment - ab160531 from Abcam

Category Protein
Source Wheat germ
Species Human
ab160531 on a 12.5% SDS-PAGE stained with Coomassie Blue.

GS28 / GOSR1 / p28 Antibody Blocking Peptide - LS-E21777 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human GOSR1 Protein - H00009527-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

GOSR1 Recombinant Protein - H00009527-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 2 µg
Species Human

GOSR1 Blocking Peptide - 33R-3986 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

GOSR1 / GS28 - H00009527-P01-10 from Acris Antibodies

Category Protein
Prices $370.00
Sizes 10 µg
Species Human

GOSR1 / GS28 - H00009527-P01-25 from Acris Antibodies

Category Protein
Prices $520.00
Sizes 25 µg
Species Human

GOSR1 / GS28 - H00009527-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

GOSR1 / GS28 - H00009527-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

GS28 fusion protein - Ag9021 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

GS28 fusion protein - Ag8997 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

Recombinant Human GS28, GST-tagged - GS28-13554H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human Golgi SNAP receptor complex member 1(GOSR1) - CSB-YP009677HU CSB-EP009677HU CSB-BP009677HU CSB-MP009677HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

GS28 Protein - abx164929 from Abbexa

Category Protein
Species Human, Mouse, Rat

GOSR1 / GS28 (transcript variant 3) - TP314955 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
GOSR1 / GS28

GOSR1 / GS28 (full length, N-term HIS tag, transcript variant 2) - TP760954 from Acris Antibodies

Category Protein
Prices $199.00
Sizes 50 µg
Source E. coli
Species Human
GOSR1 / GS28

GOSR1 Recombinant Protein Antigen - NBP1-83351PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

GOSR1-Antibody-C-term-Blocking-Peptide - BP8901b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

GOSR1 Peptide, Human - M34GP06459H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Golgi SNAP receptor complex member 1, Recombinant Protein - MBS7042817 from MyBioSource

Category Protein
Prices $1,050.00, $2,035.00, $3,245.00
Sizes 10 µg, 50 µg, 100 µg
Source Cell Free Expression
Species Caenorhabditis

Golgi SNAP receptor complex member 1, Recombinant Protein - MBS7042819 from MyBioSource

Category Protein
Prices $1,065.00, $2,050.00, $3,260.00
Sizes 10 µg, 50 µg, 100 µg
Source Cell Free Expression
Species Human

Golgi SNAP receptor complex member 1 (gos-28), Recombinant Protein - MBS1034221 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Caenorhabditis

Golgi SNAP receptor complex member 1 (GOSR1), Recombinant Protein - MBS1195094 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

Golgi SNAP receptor complex member 1 (GOSR1), Recombinant Protein - MBS1447271 from MyBioSource

Category Protein
Prices $980.00, $980.00, $1,200.00, $1,200.00, $1,480.00, $1,480.00, $1,945.00, $1,945.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Orangutan
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