Nos1

Gene Symbol	Nos1
Entrez Gene	18125
Alt Symbol	2310005C01Rik, NO, NOS-I, Nos-1, bNOS, nNOS
Species	Mouse
Gene Type	protein-coding
Description	nitric oxide synthase 1, neuronal
Other Description	N-NOS|NC-NOS|NOS type I|constitutive NOS|neuronal NOS|neuronal nitric oxide synthase|nitric oxide synthase, brain|peptidyl-cysteine S-nitrosylase NOS1
Swissprots	Q64208 Q3UR10 Q9Z0J4
Accessions	EDL19803 Q9Z0J4 AK009163 AK141904 BAE24878 BC066101 BC083183 BC167235 AAI67235 D14552 BAA03415 S81982 AAB36469 U50718 XM_006530187 XP_006530250 XM_006530188 XP_006530251 XM_006530189 XP_006530252 XM_006530190 XP_006530253 XM_006530191 XP_006530254 XM_006530192 XP_006530255 NM_008712 NP_032738
Function	Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR. Isoform NNOS Mu may be an effector enzyme for the dystrophin complex. {ECO:0000269|PubMed:17293453}.
Subcellular Location	Cell membrane, sarcolemma; Peripheral membrane protein. Cell projection, dendritic spine {ECO:0000250}. Note=In skeletal muscle, it is localized beneath the sarcolemma of fast-twitch muscle fiber by associating with the dystrophin glycoprotein complex. In neurons, enriched in dendritic spines (By similarity). {ECO:0000250}.
Tissue Specificity	Widely expressed in the nervous system: expressed in cerebrum, olfactory bulb, hippocampus, midbrain, cerebellum, pons, medulla oblongata, and spinal cord. Also found in skeletal muscle, where it is localized beneath the sarcolemma of fast twitch muscle fibers, and in spleen, heart, kidney, and liver. N-NOS-1 and N-NOS-2 are found in all parts of the nervous system. NNOS beta and gamma occur in a region-specific manner in the brain and NNOS beta expression is developmentally regulated. NNOS Mu is only found in mature skeletal and cardiac muscles.
Top Pathways	Circadian entrainment, Phagosome, Salivary secretion, Calcium signaling pathway, Amyotrophic lateral sclerosis (ALS)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Neuronal Nitric Oxide Synthase (nNOS/NOS1), Mouse, ELISA Kit - CSB-E13273m from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Neuronal Nitric Oxide Synthase, Mouse, ELISA Kit - E03N0069 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Nitric oxide synthase, brain, Nos1, Mouse, ELISA Kit - E0628m from ARP American Research Products Category ELISA Kit Prices $496.00 Sizes 96 t

Mouse NO ELISA Kit - MN0048 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Mouse NOS1/nNOS(Nitric Oxide Synthase 1, Neuronal) ELISA Kit - E-EL-M1281 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

Mouse NOS1/nNOS (Nitric Oxide Synthase 1, Neuronal) CLIA Kit - E-CL-M0697 from Elabscience Category CLIA Kit Sensitivity 18.75 pg/mL Range Average Recovery (%)

Neuronal Nitric Oxide Synthase, ELISA Kit - MBS018983 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

nitric oxide synthase 1 (neuronal) , ELISA Kit - MBS700012 from MyBioSource Category ELISA Kit Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mouse Neuronal Nitric Oxide Synthase (nNOS/NOS1) ELISA Kit - CSB-E13273m from Cusabio Category ELISA Kit Sensitivity 7.81 pg/ml Range 31.25 pg/ml-2000 pg/ml

Mouse Total Nitric Oxide ELISA - E03N0041 from BlueGene Biotech Category ELISA Kit

Mouse NOS1/nNOS(Nitric Oxide Synthase 1, Neuronal) ELISA Kit - E-EL-M1281 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.1 ng/mL Range 0.16~10 ng/mL

Mouse S100A7 (S100 Calcium Binding Protein A7) CLIA Kit - E-CL-M0599 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 0.141ng/mL Range 0.234-15ng/mL

Mouse Nitric Oxide Synthase 1, Neuronal ELISA Kit - abx254292 from Abbexa Category ELISA Kit Sensitivity 0.094 ng/ml Range 0.156 ng/ml - 10 ng/ml

Mouse nNOS ELISA Kit - abx055268 from Abbexa Category ELISA Kit Sensitivity 22 pg/ml Range 56 pg/ml - 2000 pg/ml

NOS1/nNOS (Nitric Oxide Synthase 1, Neuronal), CLIA Kit - MBS2532674 from MyBioSource Category CLIA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/mL Range 31.25-2000pg/mL

Mouse Neuronal Nitric Oxide Synthase (nNOS/NOS1) ELISA Kit - EKC37478 from Biomatik Category ELISA Kit Prices $795.00, $3,021.00, $5,645.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 7.81 pg/ml Range 31.25 pg/ml-2000 pg/ml

NOS1/nNOS - EKM2470 from Nordic BioSite Sensitivity 0.094ng/ml Range 0.156--10ng/ml

Mouse nNOS ELISA Kit - E061445 from Biobool Category ELISA Kit Sensitivity 0.1 ng/mL.

Mouse Nos1 ELISA Kit - E061705 from Biobool Category ELISA Kit

Mouse NOS1/nNOS ELISA Kit - E061816 from Biobool Category ELISA Kit Sensitivity 0.094ng/mL

Mouse NO ELISA Kit - E070447 from Biobool Category ELISA Kit Sensitivity 0.1 umol/L.

NOS1 ELISA Kit (Mouse) (OKEH05791) - OKEH05791 from Aviva Systems Biology Category ELISA Kit Prices $380.00 Sizes 96 wells Sensitivity 0.16 ng/mL Range 0.312-20 ng/mL

Mouse NO ELISA Kit - EMN0048 from ABclonal Category ELISA Kit Prices $495.00 Sizes 96 t

Nitric oxide synthase, ELISA Kit - MBS2880996 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nitric Oxide Synthase 1, Neuronal, ELISA Kit - MBS764970 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/ml Range 0.156-10ng/ml

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