Nos1

Gene Symbol	Nos1
Entrez Gene	18125
Alt Symbol	2310005C01Rik, NO, NOS-I, Nos-1, bNOS, nNOS
Species	Mouse
Gene Type	protein-coding
Description	nitric oxide synthase 1, neuronal
Other Description	N-NOS|NC-NOS|NOS type I|constitutive NOS|neuronal NOS|neuronal nitric oxide synthase|nitric oxide synthase, brain|peptidyl-cysteine S-nitrosylase NOS1
Swissprots	Q64208 Q3UR10 Q9Z0J4
Accessions	EDL19803 Q9Z0J4 AK009163 AK141904 BAE24878 BC066101 BC083183 BC167235 AAI67235 D14552 BAA03415 S81982 AAB36469 U50718 XM_006530187 XP_006530250 XM_006530188 XP_006530251 XM_006530189 XP_006530252 XM_006530190 XP_006530253 XM_006530191 XP_006530254 XM_006530192 XP_006530255 NM_008712 NP_032738
Function	Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR. Isoform NNOS Mu may be an effector enzyme for the dystrophin complex. {ECO:0000269|PubMed:17293453}.
Subcellular Location	Cell membrane, sarcolemma; Peripheral membrane protein. Cell projection, dendritic spine {ECO:0000250}. Note=In skeletal muscle, it is localized beneath the sarcolemma of fast-twitch muscle fiber by associating with the dystrophin glycoprotein complex. In neurons, enriched in dendritic spines (By similarity). {ECO:0000250}.
Tissue Specificity	Widely expressed in the nervous system: expressed in cerebrum, olfactory bulb, hippocampus, midbrain, cerebellum, pons, medulla oblongata, and spinal cord. Also found in skeletal muscle, where it is localized beneath the sarcolemma of fast twitch muscle fibers, and in spleen, heart, kidney, and liver. N-NOS-1 and N-NOS-2 are found in all parts of the nervous system. NNOS beta and gamma occur in a region-specific manner in the brain and NNOS beta expression is developmentally regulated. NNOS Mu is only found in mature skeletal and cardiac muscles.
Top Pathways	Circadian entrainment, Phagosome, Salivary secretion, Calcium signaling pathway, Amyotrophic lateral sclerosis (ALS)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Mouse NOS1 Protein - abx068301 from Abbexa Category Protein Source E.coli Species Mouse

Mouse NOS1 Protein - abx068300 from Abbexa Category Protein Source E.coli Species Mouse

Mouse NOS1 Protein - abx068298 from Abbexa Category Protein Source E.coli Species Mouse

Mouse NOS1 Protein - abx068297 from Abbexa Category Protein Source E.coli Species Mouse

Nitric Oxide Synthase 1, Neuronal (NOS1), Mouse - 20-7151 from ARP American Research Products Category Protein Prices $521.00 Sizes 50 µg Source E.coli Species Mouse

Nitric Oxide Synthase 1, Neuronal (NOS1), Mouse - 20-7152 from ARP American Research Products Category Protein Prices $521.00 Sizes 50 µg Source E.coli Species Mouse

Nitric Oxide Synthase 1, Neuronal (NOS1), Mouse - 20-7153 from ARP American Research Products Category Protein Prices $521.00 Sizes 50 µg Source E.coli Species Mouse

Nitric Oxide Synthase 1, Neuronal (NOS1), Mouse - 20-7154 from ARP American Research Products Category Protein Prices $521.00 Sizes 50 µg Source E.coli Species Mouse

Recombinant Mouse APRIL (Carrier-free) - 21-8127 from Tonbo Biosciences Category Protein Prices $67.00, $180.00, $585.00, $1,841.00 Sizes 5 µg, 20 µg, 100 µg, 500 µg Source E. coli Species Mouse

Recombinant Mouse CCL11 (Eotaxin) (Carrier-free) - 21-7014 from Tonbo Biosciences Category Protein Prices $76.00, $190.00, $625.00, $1,750.00 Sizes 5 µg, 20 µg, 100 µg, 500 µg Source E. coli Species Mouse

Recombinant Mouse GM-CSF (Carrier-free) - 21-8331 from Tonbo Biosciences Category Protein Prices $56.00, $152.00, $620.00, $1,696.00 Sizes 5 µg, 20 µg, 100 µg, 500 µg Source E. coli Species Mouse

Recombinant Mouse IL-17F (Carrier-free) - 21-8471 from Tonbo Biosciences Category Protein Prices $150.00, $236.00, $525.00, $1,547.00 Sizes 5 µg, 25 µg, 100 µg, 500 µg Source E. coli Species Mouse

Recombinant Mouse IL-21 (Carrier-free) - 21-8211 from Tonbo Biosciences Category Protein Prices $66.00, $185.00, $880.00, $2,560.00 Sizes 2 µg, 10 µg, 100 µg, 500 µg Source E. coli Species Mouse

Recombinant Mouse Thrombopoietin (TPO) (Carrier-free) - 21-8686 from Tonbo Biosciences Category Protein Prices $76.00, $175.00, $805.00, $2,495.00 Sizes 2 µg, 10 µg, 100 µg, 500 µg Source E. coli Species Mouse

Recombinant Nitric Oxide Synthase 1, Neuronal (NOS1) - RPA815Mu01 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Nitric Oxide Synthase 1, Neuronal (NOS1) - RPA815Mu02 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Nitric Oxide Synthase 1, Neuronal (NOS1) - RPA815Mu03 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Nitric Oxide Synthase 1, Neuronal (NOS1) - RPA815Mu04 from Cloud-clone Category Protein Source E.coli Species Mouse

Nitric Oxide Synthase 1, Neuronal (NOS1) - RPU143057 from Biomatik Category Protein Prices $248.60, $497.20, $745.80 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Mouse

Nitric Oxide Synthase 1, Neuronal (NOS1) - RPU143058 from Biomatik Category Protein Prices $248.60, $497.20, $745.80 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Mouse

Nitric Oxide Synthase 1, Neuronal (NOS1) - RPU143060 from Biomatik Category Protein Prices $248.60, $497.20, $745.80 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Mouse

Nitric Oxide Synthase 1, Neuronal (NOS1) - RPU143061 from Biomatik Category Protein Prices $248.60, $497.20, $745.80 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Mouse

Recombinant Mouse NOS1 Protein - NOS1-10784M from Creative Biomart Category Protein Source Mammalian Cells Species Mouse

Recombinant Nitric Oxide Synthase 1, Neuronal (NOS1) - RPU43057 from Biomatik Category Protein Prices $199.00, $389.00, $622.00, $741.28 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Mouse

Recombinant Nitric Oxide Synthase 1, Neuronal (NOS1) - RPU43058 from Biomatik Category Protein Prices $199.00, $389.00, $622.00, $741.28 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Mouse

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