Il1r2

Gene Symbol	Il1r2
Entrez Gene	16178
Alt Symbol	CD121b, Il1r-2
Species	Mouse
Gene Type	protein-coding
Description	interleukin 1 receptor, type II
Other Description	CD121 antigen-like family member B|IL-1 receptor beta chain|IL-1 type II receptor|IL-1R-2|IL-1R-beta|IL-1RT-2|IL-1RT2|interleukin-1 receptor beta|interleukin-1 receptor type 2|interleukin-1 receptor type II
Swissprots	P27931
Accessions	EDL14570 EDL14571 P27931 AK132264 BAE21067 BC032962 AAH32962 CT010182 CAJ18390 X59769 CAA42440 XM_006495724 XP_006495787 XM_006495725 XP_006495788 XM_006495726 XP_006495789 XM_011238437 XP_011236739 XM_011238438 XP_011236740 XM_011238439 XP_011236741 XM_011238440 XP_011236742 NM_010555 NP_034685
Function	Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors (By similarity). {ECO:0000250}.
Subcellular Location	Membrane; Single-pass type I membrane protein. Cell membrane {ECO:0000250}. Secreted {ECO:0000250}.
Tissue Specificity	Strongly expressed in B-cells, with levels 21 times higher than IL1R1. In T-cells expressed 5 times more compared with IL1R1. {ECO:0000269|PubMed:15986350}.
Top Pathways	Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, MAPK signaling pathway, Amoebiasis, HTLV-I infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Interleukin 1 Receptor Type II (IL1R2), Mouse, ELISA Kit - SEA065Mu from ARP American Research Products Category ELISA Kit Prices $668.00 Sizes 96 t Sensitivity 6.4pg/mL Range 15.6-1,000pg/mL

Interleukin-1 receptor type 2, IL1R2, Mouse, ELISA Kit - E0066m from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Soluble interleukin-1 receptor II, IL-1sRII, Mouse, ELISA Kit - CSB-E07447m from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.058 ng/ml Range 0.235 ng/ml-15 ng/ml

interleukin 1 receptor, type II, ELISA Kit - MBS702493 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.058 ng/ml Range 0.235 ng/ml-15 ng/ml

Mouse soluble interleukin-1 receptor Ⅱ,IL-1sRⅡ ELISA kit - CSB-E07447m from Cusabio Category ELISA Kit Sensitivity 0.058 ng/ml. Range 0.235 ng/ml-15 ng/ml

ELISA Kit for Interleukin 1 Receptor Type II (IL1R2) - SEA065Mu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 6.8pg/mL. Range 15.625-1000pg/mL The standard curve concentrations used for the ELISA's were 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL, 15.625pg/mL

Mouse IL-1R2(Interleukin 1 Receptor Type II) ELISA Kit - E-EL-M2443 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 46.88 pg/mL Range 78.13~5000 pg/mL

Mouse IL1R2 ELISA Kit - abx154195 from Abbexa Category ELISA Kit Range 15.63 pg/ml - 1000 pg/ml

Interleukin 1 Receptor Type II (IL1R2), Mouse, ELISA Kit - DL-IL1R2-Mu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Range 15.6-1,000 pg/mL

Mouse IL1R2 ELISA Kit - orb366551 from Biorbyt Category ELISA Kit Prices $459.00, $621.00 Sizes 48 test, 96 test Range Detection Range: 15.625-1000pg/mL Detection low threshold: 6.4pg/mL

Interleukin 1 Receptor Type II, IL-1R2, Mouse, ELISA Kit - E-EL-M2443 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 46.875 Range 78.125-5000pg/mL

Mouse IL1R2 ELISA Kit - abx574671 from Abbexa Category ELISA Kit Sensitivity 6.4 pg/ml Range 15.625 pg/ml - 1000 pg/ml

Mouse Il1r2 ELISA Kit - E057145 from Biobool Category ELISA Kit

IL1R2 ELISA Kit (Mouse) (OKCD02631) - OKCD02631 from Aviva Systems Biology Category ELISA Kit Prices $515.00 Sizes 1 ng Sensitivity 6.4 pg/mL Range 15.62-1,000 pg/mL

Interleukin 1 Receptor Type II (IL1R2), ELISA Kit - MBS455795 from MyBioSource Category ELISA Kit Prices $355.00, $465.00, $1,995.00, $3,870.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <11.38pg/mL Range 31.25-2000pg/mL

Interleukin-1 receptor type 2, ELISA Kit - MBS289644 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

IL1R2 ELISA Kit (Mouse) (OKCA02191) - OKCA02191 from Aviva Systems Biology Category ELISA Kit Sensitivity 0.058 ng/mL Range 0.235 ng/mL-15 ng/mL

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