PVRL4

Gene Symbol PVRL4
Entrez Gene 81607
Alt Symbol EDSS1, LNIR, PRR4, nectin-4
Species Human
Gene Type protein-coding
Description poliovirus receptor-related 4
Other Description Ig superfamily receptor LNIR|nectin 4|nectin-4|poliovirus receptor-related protein 4
Swissprots B4DQW3 Q96K15 Q96NY8
Accessions CDM63684 CDM63771 CDM63773 CDM63774 CDM63775 CDM63777 CDM63778 EAW52665 EAW52666 Q96NY8 AB105191 BAQ19759 AB755430 BAM65001 AF160477 AAF82399 AF218028 AAG17270 AF426163 AAL23958 AK027753 BAB55344 AK298981 BAG61075 AK301481 BAG62996 BC010423 AAH10423 BC013892 BX641083 CF529301 DB223835 DQ893504 ABM84430 DQ896483 ABM87482 XM_005245508 XP_005245565 XM_011510021 XP_011508323 XM_011510022 XP_011508324 XM_011510023 XP_011508325 NM_030916 NP_112178
Function Seems to be involved in cell adhesion through trans- homophilic and -heterophilic interactions, the latter including specifically interactions with PVRL2/nectin-1. Does not act as receptor for alpha-herpesvirus entry into cells.
Subcellular Location Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cell junction, adherens junction {ECO:0000269|PubMed:11544254}. Note=Colocalizes with MLLT4 at cadherin-based adherens junctions.
Tissue Specificity Predominantly expressed in placenta. Not detected in normal breast epithelium but expressed in breast carcinoma. {ECO:0000269|PubMed:11544254, ECO:0000269|PubMed:17474988}.
Top Pathways Adherens junction

Nectin 4 (T-14) - sc-54680 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PVRL4 [EPR15613-68] antibody - ab192033 from Abcam

Prices $355.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15613-68
All lanes : Anti-PVRL4 [EPR15613-68] antibody (ab192033) at 1/1000 dilutionLane 1 : T47D lysateLane 2 : MCF7 lysateLane 3 : Human placenta lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-PVRL4 antibody - ab155692 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PVRL4 antibody (ab155692) at 1/1000 dilution + Raji whole cell lysate at 30 µg

Anti-PVRL4 antibody - ab110387 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PVRL4 antibody (ab110387) at 1/500 dilutionLane 1 : extracts from NIH/3T3 cellsLane 2 : extracts from NIH/3T3 cells with blocking peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-PVRL4 antibody - ab173611 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PVRL4 antibody (ab173611) at 1/100 dilution + A2058 cell lysate at 35 µg

Anti-PVRL4 antibody - ab57873 from Abcam

Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57873 PVRL4 antibody at 1ug/ml.

Anti-PVRL4 antibody [EPR15613] - ab189514 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15613
All lanes : Anti-PVRL4 antibody [EPR15613] (ab189514) at 1/1000 dilutionLane 1 : T47D cell lysateLane 2 : MCF7 cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Anti-PVRL4 / Nectin 4 Antibody (aa27-351) - LS-C37483 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-PVRL4 / Nectin 4 Antibody - LS-C37484 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rat
Clonality Monoclonal

Anti-PVRL4 / Nectin 4 Antibody (aa238-266, AP) - LS-C239628 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PVRL4 / Nectin 4 Antibody (aa238-266, APC) - LS-C239629 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PVRL4 / Nectin 4 Antibody (aa238-266, Biotin) - LS-C239630 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PVRL4 / Nectin 4 Antibody (aa238-266, FITC) - LS-C239631 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PVRL4 / Nectin 4 Antibody (aa238-266, PE) - LS-C239632 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PVRL4 / Nectin 4 Antibody (aa238-266, Azide-free, HRP) - LS-C248589 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PVRL4 / Nectin 4 Antibody (aa238-266) - LS-C330044 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PVRL4 / Nectin 4 Antibody (aa27-351) - LS-C150011 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Nectin-4 in Human Placenta. Nectin-4 was detected in immersion fixed paraffin-embedded sections of human placenta using 10 ug/ml Goat Anti-Human Nectin-4 Antigen Affinity-purified Polyclonal Antibody overnight at 4°C. Before incubation with the primary antibody tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic. Tissue was stained with Anti-Goat HRP-DAB (brown) and counterstained with hematoxylin (blue).

Anti-PVRL4 / Nectin 4 Antibody (aa238-266) - LS-C158771 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PVRL4 Antibody western blot of A2058 cell line lysates (35 ug/lane). The PVRL4 antibody detected the PVRL4 protein (arrow).

Anti-PVRL4 / Nectin 4 Antibody (aa312-361) - LS-C120225 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from NIH-3T3 cells, using PVRL4 Antibody. The lane on the right is treated with the synthesized peptide.

Nectin-4/PVRL4 Antibody [Unconjugated] - AF2659 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Nectin‑4 was detected in immersion fixed paraffin-embedded sections of human placenta using 10 µg/mL Goat Anti-Human Nectin‑4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2659) overnight at 4 °C. Before incubation with the primary antibody tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

Nectin-4/PVRL4 Antibody (337516) - MAB2659 from Novus Biologicals

Prices $249.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 337516

Nectin-4/PVRL4 Antibody - NBP1-82829 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Nectin-4/PVRL4 Antibody [NBP1-82829] - Analysis in control (vector only transfected HEK293T lysate) and PVRL4 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

Nectin-4/PVRL4 Antibody - NBP2-20014 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PVRL4 Antibody [NBP2-20014] - Sample (30 ug of whole cell lysate) A: Raji 7. 5% SDS PAGE gel, diluted at 1:1000.

Nectin-4/PVRL4 Antibody - H00081607-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: Nectin-4/PVRL4 Antibody [H00081607-B01] - analysis of PVRL4 expression in transfected 293T cell line by PVRL4 MaxPab polyclonal antibody (B01). Lane 1: PVRL4 transfected lysate (55.50 KDa). Lane 2: Non-transfected lysate.

Nectin-4/PVRL4 Antibody (1D7) - H00081607-M01A from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone 1D7
Search more