PVRL4

Gene Symbol PVRL4
Entrez Gene 81607
Alt Symbol EDSS1, LNIR, PRR4, nectin-4
Species Human
Gene Type protein-coding
Description poliovirus receptor-related 4
Other Description Ig superfamily receptor LNIR|nectin 4|nectin-4|poliovirus receptor-related protein 4
Swissprots B4DQW3 Q96K15 Q96NY8
Accessions CDM63684 CDM63771 CDM63773 CDM63774 CDM63775 CDM63777 CDM63778 EAW52665 EAW52666 Q96NY8 AB105191 BAQ19759 AB755430 BAM65001 AF160477 AAF82399 AF218028 AAG17270 AF426163 AAL23958 AK027753 BAB55344 AK298981 BAG61075 AK301481 BAG62996 BC010423 AAH10423 BC013892 BX641083 CF529301 DB223835 DQ893504 ABM84430 DQ896483 ABM87482 XM_005245508 XP_005245565 XM_011510021 XP_011508323 XM_011510022 XP_011508324 XM_011510023 XP_011508325 NM_030916 NP_112178
Function Seems to be involved in cell adhesion through trans- homophilic and -heterophilic interactions, the latter including specifically interactions with PVRL2/nectin-1. Does not act as receptor for alpha-herpesvirus entry into cells.
Subcellular Location Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cell junction, adherens junction {ECO:0000269|PubMed:11544254}. Note=Colocalizes with MLLT4 at cadherin-based adherens junctions.
Tissue Specificity Predominantly expressed in placenta. Not detected in normal breast epithelium but expressed in breast carcinoma. {ECO:0000269|PubMed:11544254, ECO:0000269|PubMed:17474988}.
Top Pathways Adherens junction

Human PVRL4 / Nectin 4 ELISA Kit (Sandwich ELISA) - LS-F6329 from LifeSpan Bioscience

Category ELISA Kit
Prices $720.00
Sizes 1 plate
Sensitivity 51 pg/ml
Range 125-8000 pg/ml

Human Nectin-4 DuoSet ELISA - DY2659 from R&D Systems

Category ELISA Kit
Prices $649.00
Sizes 1 kit (for 15 Plates)
Range 93.80 - 6,000 pg/mL

Quantikine Immunoassay Control Set 803 for Human Nectin-4 - QC133 from R&D Systems

Category ELISA Kit
Prices $125.00
Sizes 1 each

Human Nectin-4 Quantikine ELISA Kit - DNEC40 from R&D Systems

Category ELISA Kit
Prices $509.00
Sizes 1 kit
Sensitivity 16.6 pg/mL
Range 39.1 - 2,500 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Urine)
Human Nectin-4 Quantikine ELISA Kit

Custom Human Nectin-4 ELISA - ELH-NEC4 from RayBiotech

Category ELISA Kit
Prices $615.00, $1,107.00, $2,460.00
Sizes 1 plate kit, 2 plate kit, 5 plate kit

PRR4, ELISA Kit - MBS2507961 from MyBioSource

Category ELISA Kit
Prices $410.00, $490.00, $2,040.00, $3,590.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.188ng/mL
Range 0.313--20ng/mL

Poliovirus Receptor Related Protein 4 (PVRL4), ELISA Kit - MBS2023682 from MyBioSource

Category ELISA Kit
Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00
Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity Typically less than 51pg/mL.
Range 125-8000pg/mL

ELISA Kit for Poliovirus Receptor Related Protein 4 (PVRL4) - SEC757Hu from Uscn Life Science Inc.

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 51pg/mL.
Range 125-8000pg/mL The standard curve concentrations used for the ELISA’s were 8000pg/mL, 4000pg/mL, 2000pg/mL, 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL

Human PVRL4 ELISA Kit - abx152902 from Abbexa

Category ELISA Kit
Sensitivity 52 pg/ml
Range 125 pg/ml - 8000 pg/ml

Poliovirus Receptor Related Protein 4 (PVRL4), Human, ELISA Kit - DL-PVRL4-Hu from ARP American Research Products

Category ELISA Kit
Prices $655.00
Sizes 96 t
Range 125-8,000 pg/mL

Human Nectin-4 ELISA Kit - orb371803 from Biorbyt

Category ELISA Kit
Prices $612.00
Sizes 96 well
Sensitivity <10pg/ml
Range 31.2pg/ml-2000pg/ml

Human PVRL4 ELISA Kit - abx574344 from Abbexa

Category ELISA Kit
Sensitivity 52 pg/ml
Range 125 pg/ml - 8000 pg/ml

Human Nectin-4 ELISA - RAB1589 from Sigma-Aldrich

Prices $615.00
Sizes 1 kt

Human Nectin-4 ELISA Kit - NR-E10323 from Novatein Biosciences

Category ELISA Kit
Prices $359.00
Sizes 1x96t
Range 93.75 -6000pg/ml

Human Nectin-4/PVRL4 PicoKine™ ELISA Kit EK1536 - EK1536 from Boster Bio

Category ELISA Kit
Prices $369.00
Sizes 1 kit
Sensitivity <10pg/ml
Range 31.2pg/ml-2000pg/ml *This assay range is determined using common samples. For samples with low target protein concentrations, users can adjust the standard curve to extend the lower limit of assay range.
Human Nectin-4/PVRL4 PicoKine™ ELISA Kit

Human Nectin 4 ELISA Kit - CEK1873 from Cohesion Biosciences

Category ELISA Kit
Prices $380.00
Sizes 96 t
Sensitivity 10 pg/ml
Range 31.2 pg/ml - 2000 pg/ml
Representative Standard Curve

Custom Human Nectin-4 ELISA - ELH-NEC4-1 from RayBiotech

Category ELISA Kit
Prices $627.00, $1,128.60, $2,508.00
Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human PVRL4 ELISA Kit - E029977 from Biobool

Category ELISA Kit
Sensitivity Typically less than 51pg/mL.

NECTIN4 ELISA Kit (Human) (OKCD01698) - OKCD01698 from Aviva Systems Biology

Category ELISA Kit
Prices $545.00
Sizes 96 wells
Sensitivity < 51 pg/mL
Range 125.00 - 8,000 pg/mL

Human Poliovirus receptor-related protein 4 (PVRL4) ELISA Kit - AE24962HU from ARP American Research Products

Category ELISA Kit
Prices $549.00
Sizes 96 t
Sensitivity 51 pg/mL
Range 125.00-8000 pg/mL

Nectin 4, ELISA Kit - MBS8248380 from MyBioSource

Category ELISA Kit
Prices $490.00
Sizes 96 tests
Sensitivity <10 pg/ml

Nectin-4, ELISA Kit - MBS178569 from MyBioSource

Category ELISA Kit
Prices $425.00
Sizes 1x96 wells
Sensitivity <10pg/ml
Range 31.2pg/ml-2000pg/ml

Poliovirus Receptor Related Protein 4 (PVRL4), ELISA Kit - MBS452053 from MyBioSource

Category ELISA Kit
Prices $415.00, $550.00, $2,425.00, $4,710.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity <52pg/mL
Range 125-8000pg/mL

Human PVRL4 / Nectin 4 ELISA Kit (Sandwich ELISA) - LS-F39985 from LifeSpan Bioscience

Category ELISA Kit
Sensitivity 10 pg/ml
Range 125-8000 pg/ml

Human PVRL4 / Nectin 4 ELISA Kit (Sandwich ELISA) - LS-F31677 from LifeSpan Bioscience

Category ELISA Kit
Sensitivity 10 pg/ml
Range 125-8000 pg/ml
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