PVRL4

Gene Symbol	PVRL4
Entrez Gene	81607
Alt Symbol	EDSS1, LNIR, PRR4, nectin-4
Species	Human
Gene Type	protein-coding
Description	poliovirus receptor-related 4
Other Description	Ig superfamily receptor LNIR|nectin 4|nectin-4|poliovirus receptor-related protein 4
Swissprots	B4DQW3 Q96K15 Q96NY8
Accessions	CDM63684 CDM63771 CDM63773 CDM63774 CDM63775 CDM63777 CDM63778 EAW52665 EAW52666 Q96NY8 AB105191 BAQ19759 AB755430 BAM65001 AF160477 AAF82399 AF218028 AAG17270 AF426163 AAL23958 AK027753 BAB55344 AK298981 BAG61075 AK301481 BAG62996 BC010423 AAH10423 BC013892 BX641083 CF529301 DB223835 DQ893504 ABM84430 DQ896483 ABM87482 XM_005245508 XP_005245565 XM_011510021 XP_011508323 XM_011510022 XP_011508324 XM_011510023 XP_011508325 NM_030916 NP_112178
Function	Seems to be involved in cell adhesion through trans- homophilic and -heterophilic interactions, the latter including specifically interactions with PVRL2/nectin-1. Does not act as receptor for alpha-herpesvirus entry into cells.
Subcellular Location	Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cell junction, adherens junction {ECO:0000269|PubMed:11544254}. Note=Colocalizes with MLLT4 at cadherin-based adherens junctions.
Tissue Specificity	Predominantly expressed in placenta. Not detected in normal breast epithelium but expressed in breast carcinoma. {ECO:0000269|PubMed:11544254, ECO:0000269|PubMed:17474988}.
Top Pathways	Adherens junction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PVRL4 full length protein - ab164347 from Abcam Category Protein Source Wheat germ Species Human

Human PVRL4 protein fragment - ab164348 from Abcam Category Protein Source Wheat germ Species Human

PVRL4 / Nectin 4 Antibody Blocking Peptide - LS-E5412 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Nectin-4/PVRL4 Protein - H00081607-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human Nectin-4/PVRL4 Protein - H00081607-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PVRL4-Antibody-Center-Blocking-Peptide - BP17922c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Nectin-4, CF - 2659-N4-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Gly27-Val351, with a C-terminal 6-His tag

Yeast PVRL4 protein - orb246179 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Yeast

PVRL4 / Nectin 4 - H00081607-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

PVRL4 / Nectin 4 - H00081607-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PVRL4 / Nectin 4 - H00081607-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

nectin 4 fusion protein - Ag14127 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

nectin 4 fusion protein - ag14414 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human PVRL4, GST-tagged - PVRL4-2081H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human PVRL4, His-tagged - PVRL4-776H from Creative Biomart Category Protein Source NSO Cells Species Human

Recombinant Poliovirus Receptor Related Protein 4 (PVRL4) - RPC757Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Human Poliovirus receptor-related protein 4(PVRL4) - CSB-EP822274HU CSB-BP822274HU CSB-MP822274HU from Cusabio Category Protein Source E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Poliovirus receptor-related protein 4(PVRL4) - CSB-YP822274HU from Cusabio Category Protein Source Yeast Species Human

Recombinant Human Nectin-4 Protein, CF - 2659-N4 from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Mouse myeloma cell line, NS0-derived Gly27-Val351, with a C-terminal 6-His tag Species Human

PVRL4 / Nectin 4 - TP303431 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Poliovirus receptor-related protein 4, Recombinant Protein - MBS1322451 from MyBioSource Category Protein Prices $190.00, $460.00, $750.00, $1,080.00, $1,180.00, $1,305.00, $1,305.00, $1,690.00, $2,155.00, $2,155.00 Sizes 50 µg (E-Coli), 200 µg (E-Coli), 500 µg (E-Coli), 50 µg (Baculovirus), 1 mg (E-Coli), 500 µg (Yeast), 50 µg (Mammalian-Cell), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Nectin-4/PVRL4 Recombinant Protein Antigen - NBP1-82829PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Human Poliovirus Receptor-Related Protein 4 protein (C-His) - orb311905 from Biorbyt Category Protein Prices $255.00, $451.00, $1,411.00, $2,108.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

PVRL4 Peptide, Human - M34GP12761H from Creative Peptides Category Peptide Source Synthetic. Species Human

PVRL4 Recombinant Protein (OPCA03049) - OPCA03049 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

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