HLA-DMB

Gene Symbol HLA-DMB
Entrez Gene 3109
Alt Symbol D6S221E, RING7
Species Human
Gene Type protein-coding
Description major histocompatibility complex, class II, DM beta
Other Description HLA class II histocompatibility antigen, DM beta chain|MHC class II HLA-DMB|MHC class II antigen DMB|MHC class II antigen HLA-DM beta chain|class II histocompatibility antigen, M beta chain|really interesting new gene 7 protein
Swissprots Q5SNZ8 Q58ZE2 Q13012 P28068 Q29751 O77936 Q5STC4 Q9XRX2
Accessions AAA03296 AAB61609 AAC26112 AAC50514 AAC50515 AAC50517 AAD30279 AAX84974 AHW47928 AHW47945 AHW47962 AHW47979 CAA54171 CAA60782 EAX03657 P28068 AB209577 BAD92814 AB362554 BAF81534 AB362555 BAF81535 AB362556 BAF81536 AK295872 BAG58670 AK301017 BAG62634 AK315979 BAH14350 AY645722 AAV97947 BC017508 BC027175 AAH27175 BC035650 CD742571 CR407606 CAG28534 DC389968 DQ891141 ABM82067 DQ894320 ABM85246 EL948395 U15085 AAB60387 Z23139 CAA80670 NM_002118 NP_002109
Function Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO. {ECO:0000269|PubMed:16547258, ECO:0000269|PubMed:8849454, ECO:0000269|PubMed:9768757}.
Subcellular Location Late endosome membrane {ECO:0000269|PubMed:8757605}; Single-pass type I membrane protein {ECO:0000269|PubMed:8757605}. Lysosome membrane {ECO:0000269|PubMed:8757605}; Single-pass type I membrane protein {ECO:0000269|PubMed:8757605}. Note=Localizes to late endocytic compartment. Associates with lysosome membranes.
Top Pathways Leishmaniasis, HTLV-I infection, Influenza A, Tuberculosis, Herpes simplex infection

HLA-DMβ (L-14) - sc-14539 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HLA-DMb (L-14): sc-14539. Western blot analysis of HLA-DMb expression in non-transfected: sc-117752 (A) and human HLA-DMb transfected: sc-113692 (B) 293T whole cell lysates.

HLA-DMβ (K-20) - sc-14540 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HLA-DMβ (K-20): sc-14540. Western blot analysis of HLA-DMβ expression in non-transfected: sc-117750 (A) and human HLA-DMβ transfected: sc-113692 (B) whole cell lysates.

HLA-DMβ (DM.K8) - sc-69738 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Anti-HLA DMB antibody - ab191445 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HLA DMB antibody (ab191445) at 0.5 µg/mlLane 1 : Jurkat cell lysateLane 2 : Jurkat cell lysateLane 3 : Raji cell lysateLane 4 : HUT cell lysate

Anti-HLA DMB antibody - ab129661 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-HLA DMB antibody (ab129661) at 1/100 dilution + Ramos cell line lysates at 35 µgdeveloped using the ECL technique

Anti-HLA DMB antibody - ab171917 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HLA DMB antibody (ab171917) at 1 µlLane 1 : HLA DMB-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Rabbit IgG (H+L) at 1/7500 dilutiondeveloped using the ECL technique

Anti-HLA DMB antibody - ab125387 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HLA DMB antibody - ab55150 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab55150 HLA DMB antibody at 1ug/ml.

Anti-HLA DMB antibody [EPR7981] - ab133640 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7981
All lanes : Anti-HLA DMB antibody [EPR7981] (ab133640) at 1/1000 dilutionLane 1 : Raji lysateLane 2 : Daudi lysateLane 3 : Human spleen lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-HLA DMB antibody [EPR7982] - ab131273 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7982
All lanes : Anti-HLA DMB antibody [EPR7982] (ab131273) at 1/1000 dilutionLane 1 : Raji cell lysateLane 2 : Daudi cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-HLA-DMB Antibody (aa40-89) - LS-C146442 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HLA-DMB antibody Western Blot of Human Placenta. Antibody dilution: 1 ug/ml.

Anti-HLA-DMB Antibody (C-Terminus, clone EPR7982) - LS-C154502 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7982
IHC of paraffin-embedded human tonsil tissue using anti-HLA-DMB antibody.

Anti-HLA-DMB Antibody (aa199-263) - LS-C185993 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded Colon ca using HLA-DMB antibody at 1:250 dilution.

Anti-HLA-DMB Antibody (aa81-100) - LS-C312935 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
HLA-DMB antibody. IHC(P): Human Breast Cancer Tissue.

Anti-HLA-DMB Antibody (clone 6B3) - LS-C197414 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6B3

Anti-HLA-DMB Antibody (aa104-133, AP) - LS-C258585 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HLA-DMB Antibody (aa104-133, APC) - LS-C258588 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HLA-DMB Antibody (aa104-133, Biotin) - LS-C258589 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HLA-DMB Antibody (aa104-133, FITC) - LS-C258590 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HLA-DMB Antibody (aa104-133, PE) - LS-C258592 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HLA-DMB Antibody (aa104-133, Azide-free, HRP) - LS-C258591 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HLA-DMB Antibody (aa127-154, AP) - LS-C258593 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HLA-DMB Antibody (aa127-154, APC) - LS-C258594 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HLA-DMB Antibody (aa127-154, Biotin) - LS-C258595 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HLA-DMB Antibody (aa127-154, Azide-free, HRP) - LS-C258597 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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