Ada

Gene Symbol	Ada
Entrez Gene	24165
Alt Symbol	-
Species	Rat
Gene Type	protein-coding
Description	adenosine deaminase
Other Description	adenosine aminohydrolase
Swissprots	Q920P6
Accessions	CBX85548 CBX85616 EDL96561 EDL96562 Q920P6 AB059655 BAB69691 BC088116 AAH88116 NM_130399 NP_569083
Function	Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte- epithelial cell adhesion (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Extracellular side {ECO:0000250}. Cell junction {ECO:0000250}. Cytoplasmic vesicle lumen {ECO:0000269|PubMed:19900420, ECO:0000269|PubMed:8783262}. Cytoplasm {ECO:0000250}. Note=Colocalized with DPP4 at the cell junction in lymphocyte-epithelial cell adhesion. {ECO:0000250}.
Tissue Specificity	Detected in brain and liver (at protein level). {ECO:0000269|PubMed:19900420, ECO:0000269|PubMed:8783262}.
Top Pathways	Primary immunodeficiency, Purine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Rat Ada cDAN Clone(NM_130399.2) - CDFR013874 from Creative Biomart Species Rat Accession NM_130399.2

Rat Ada ORF Clone(NM_130399.2) - CDCR380908 from Creative Biomart Species Rat Accession NM_130399.2

Rat ADA / Adenosine deaminase Gene ORF cDNA clone in cloning vector - RG80863-U from Sino Biological Species Rat

Rat ADA / Adenosine deaminase Gene ORF cDNA clone expression plasmid, C-HA tag - RG80863-CY from Sino Biological Species Rat

Rat ADA / Adenosine deaminase Gene ORF cDNA clone expression plasmid, C-Flag tag - RG80863-CF from Sino Biological Species Rat

Rat ADA / Adenosine deaminase Gene ORF cDNA clone expression plasmid, N-HA tag - RG80863-NY from Sino Biological Species Rat

Rat ADA / Adenosine deaminase Gene ORF cDNA clone expression plasmid, N-Flag tag - RG80863-NF from Sino Biological Species Rat

Rat ADA / Adenosine deaminase Gene ORF cDNA clone expression plasmid, C-His tag - RG80863-CH from Sino Biological Species Rat

Rat ADA / Adenosine deaminase Gene ORF cDNA clone expression plasmid - RG80863-UT from Sino Biological Species Rat

Rat ADA / Adenosine deaminase Gene ORF cDNA clone expression plasmid, N-His tag - RG80863-NH from Sino Biological Species Rat

Rat ADA / Adenosine deaminase Gene ORF cDNA clone expression plasmid, N-Myc tag - RG80863-NM from Sino Biological Species Rat

Rat ADA / Adenosine deaminase Gene ORF cDNA clone expression plasmid, C-Myc tag - RG80863-CM from Sino Biological Species Rat

Rat ADA / Adenosine deaminase Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - RG80863-ACG from Sino Biological Species Rat

Rat ADA / Adenosine deaminase Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - RG80863-ACR from Sino Biological Species Rat

Rat Ada ORF Clone(NM_130399.2) - CDCR380908 from Creative biogene Species Rat

Rat Ada cDNA Clone(NM_130399.2) - CDFR013874 from Creative biogene Species Rat

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