Ada

Gene Symbol	Ada
Entrez Gene	24165
Alt Symbol	-
Species	Rat
Gene Type	protein-coding
Description	adenosine deaminase
Other Description	adenosine aminohydrolase
Swissprots	Q920P6
Accessions	CBX85548 CBX85616 EDL96561 EDL96562 Q920P6 AB059655 BAB69691 BC088116 AAH88116 NM_130399 NP_569083
Function	Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte- epithelial cell adhesion (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Extracellular side {ECO:0000250}. Cell junction {ECO:0000250}. Cytoplasmic vesicle lumen {ECO:0000269|PubMed:19900420, ECO:0000269|PubMed:8783262}. Cytoplasm {ECO:0000250}. Note=Colocalized with DPP4 at the cell junction in lymphocyte-epithelial cell adhesion. {ECO:0000250}.
Tissue Specificity	Detected in brain and liver (at protein level). {ECO:0000269|PubMed:19900420, ECO:0000269|PubMed:8783262}.
Top Pathways	Primary immunodeficiency, Purine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Recombinant Rat Adenosine deaminase(Ada) - CSB-YP001268RA CSB-EP001268RA CSB-BP001268RA CSB-MP001268RA from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Rat

Adenosine deaminase (add) - MBS1336269 from MyBioSource Category Protein Prices $1,765.00, $1,765.00, $2,230.00, $2,230.00 Sizes 1 mg (E Coli Derived), 100 µg (Baculovirus Derived), 1 mg (Yeast Derived), 100 µg (Mammalian Cell Derived) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Rat

Recombinant Rat ADA Protein - ADA-499R from Creative Biomart Category Protein Source Mammalian Cells Species Rat

Search more