Sema4d

Gene Symbol	Sema4d
Entrez Gene	20354
Alt Symbol	CD100, Semacl2, Semaj, Semcl2, coll-4
Species	Mouse
Gene Type	protein-coding
Description	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
Other Description	M-sema G|sema J|semaphorin H|semaphorin-4D|semaphorin-C-like 2|semaphorin-J
Swissprots	Q6GTM9 O09126
Accessions	EDL41105 EDL41106 EDL41107 O09126 AK088653 BAC40480 AK132688 BAE21302 AK150911 BC027681 BC049780 AAH49780 BE692125 U69535 AAC52964 XM_006516883 XP_006516946 XM_006516884 XP_006516947 XM_006516885 XP_006516948 XM_006516886 XP_006516949 XM_006516887 XP_006516950 XM_006516888 XP_006516951 XM_006516891 XP_006516954 XM_006516892 XP_006516955 NM_001281880 NP_001268809 NM_013660 NP_038688
Function	Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Strongly expressed in lymphoid tissues, especially in the thymus, as well as in the nervous tissues.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Semaphorin 4D/CD100 Antibody - AF5235 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Sheep Clonality Polyclonal

Semaphorin 4D/CD100 Antibody (547406) - MAB5235 from Novus Biologicals Prices $99.00, $249.00 Sizes 25 µg, 100 µg Host Rat Clonality Monoclonal Clone 547406

Semaphorin 4D/CD100 Antibody (547412) - MAB52351 from Novus Biologicals Prices $99.00, $249.00 Sizes 25 µg, 100 µg Host Rat Clonality Monoclonal Clone 547412

Semaphorin 4D/CD100 Antibody [Biotin] - BAF5235 from Novus Biologicals Prices $390.00 Sizes 50 µg Host Sheep Clonality Polyclonal

Semaphorin 4D/CD100 Antibody (547412) [Phycoerythrin] - FAB52351P from Novus Biologicals Prices $249.00 Sizes 100 tests Host Rat Clonality Monoclonal Clone 547412

Semaphorin 4D/CD100 Antibody (547412) [PerCP (Peridinin-chlorophyll Protein Complex)] - FAB52351C from Novus Biologicals Prices $299.00 Sizes 100 tests Host Rat Clonality Monoclonal Clone 547412

Semaphorin 4D/CD100 Antibody (547412) [Alexa Fluor 488] - FAB52351G from Novus Biologicals Prices $109.00 Sizes 25 tests Host Rat Clonality Monoclonal Clone 547412

CD100 / SEMA4D antibody - AM26488AF-N from Acris Antibodies Prices $260.00 Sizes 100 µg Host Rat Clonality Monoclonal Clone MMA-12

CD100 / SEMA4D antibody - AM26488FC-N from Acris Antibodies Prices $280.00 Sizes 50 µg Host Rat Clonality Monoclonal Clone MMA-12

APC anti-mouse CD100 (SEMA4D) Antibody - 147605 from Biolegend Prices $135.00, $305.00 Sizes 25 µg, 100 µg Host Rat Clone BMA-12

FITC anti-mouse CD100 (SEMA4D) Antibody - 147607 from Biolegend Prices $85.00, $205.00 Sizes 25 µg, 100 µg Host Rat Clone BMA-12

PE anti-mouse CD100 (SEMA4D) Antibody - 147603 from Biolegend Prices $125.00, $275.00 Sizes 25 µg, 100 µg Host Rat Clone BMA-12

Purified anti-mouse CD100 (SEMA4D) Antibody - 147601 from Biolegend Prices $85.00, $265.00 Sizes 25 µg, 100 µg Host Rat Clone BMA-12

BD Pharmingen™ PE Rat Anti-Mouse CD100 (Sema4D) - 565556 from BD Biosciences Prices $165.00 Sizes 50 µg Host Rat Clonality Monoclonal Clone BMA-12

Semaphorin 4D / SEMA4D / CD100 Antibody, Rabbit PAb - 50642-RP01-100 from Sino Biological Host Rabbit Clonality Polyclonal

Semaphorin 4D / SEMA4D / CD100 Antibody, Rabbit PAb, Antigen Affinity Purified - 50642-RP02-50 from Sino Biological Prices $99.00, $99.00, $99.00 Sizes 50 µg, 100 µg, 200 µg Host Rabbit Clonality Polyclonal

Semaphorin 4D / SEMA4D / CD100 Antibody (PE), Rabbit MAb - 50642-R010-P-100 from Sino Biological Prices $240.00, $240.00 Sizes 50 tests, 100 tests Host Rabbit Clonality Monoclonal Clone 010

Semaphorin 4D / SEMA4D / CD100 Antibody, Rabbit MAb - 50642-R010-100 from Sino Biological Prices $119.00, $119.00 Sizes 50 µg, 100 µg Host Rabbit Clonality Monoclonal Clone 010

Semaphorin 4D / SEMA4D / CD100 Antibody (FITC), Rabbit MAb - 50642-R010-F-100 from Sino Biological Prices $190.00, $190.00 Sizes 50 tests, 100 tests Host Rabbit Clonality Monoclonal Clone 010

Semaphorin 4D / SEMA4D / CD100 Antibody (APC), Rabbit MAb - 50642-R010-A-50 from Sino Biological Prices $130.00, $130.00 Sizes 50 tests, 100 tests Host Rabbit Clonality Monoclonal Clone 010

Anti-Semaphorin 4D/CD100 Antibody, clone BMA-12 - MABC987 from EMD Millipore Prices $299.00 Sizes 100 µg Host Rat Clonality Monoclonal Clone BMA-12

Anti-Mouse CD100 (SEMA4D) Biotin - 13-1001 from eBioscience Prices $199.00 Sizes 100 µg Host Rat Clonality Monoclonal Clone BMA12 (BMA-12)

Anti-Mouse CD100 (SEMA4D) FITC - 11-1001 from eBioscience Prices $119.00, $209.00 Sizes 50 µg, 100 µg Host Rat Clonality Monoclonal Clone BMA12 (BMA-12)

Anti-Mouse CD100 (SEMA4D) Functional Grade Purified (Discontinued) - 16-1001 from eBioscience Host Rat Clonality Monoclonal Clone BMA12 (BMA-12)

Anti-Mouse CD100 (SEMA4D) Purified - 14-1001 from eBioscience Prices $269.00 Sizes 100 µg Host Rat Clonality Monoclonal Clone BMA12 (BMA-12)

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