Sema4d

Gene Symbol	Sema4d
Entrez Gene	20354
Alt Symbol	CD100, Semacl2, Semaj, Semcl2, coll-4
Species	Mouse
Gene Type	protein-coding
Description	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
Other Description	M-sema G|sema J|semaphorin H|semaphorin-4D|semaphorin-C-like 2|semaphorin-J
Swissprots	Q6GTM9 O09126
Accessions	EDL41105 EDL41106 EDL41107 O09126 AK088653 BAC40480 AK132688 BAE21302 AK150911 BC027681 BC049780 AAH49780 BE692125 U69535 AAC52964 XM_006516883 XP_006516946 XM_006516884 XP_006516947 XM_006516885 XP_006516948 XM_006516886 XP_006516949 XM_006516887 XP_006516950 XM_006516888 XP_006516951 XM_006516891 XP_006516954 XM_006516892 XP_006516955 NM_001281880 NP_001268809 NM_013660 NP_038688
Function	Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Strongly expressed in lymphoid tissues, especially in the thymus, as well as in the nervous tissues.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Semaphorin-4D (SEMA4D), Mouse, ELISA Kit - CSB-EL020990MO from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Semaphorin-4D, Sema4d, Mouse, ELISA Kit - E2275m from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Mouse CD100(Cluster of Differentiation 100) ELISA Kit - E-EL-M0301 from Elabscience Category ELISA Kit Sensitivity 0.19 ng/mL Range 0.31—20 ng/mL

CD100, ELISA Kit - MBS2506577 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313-20ng/mL

sema domain, immunoglobulin domain (Ig) , transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D, ELISA Kit - MBS932666 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of mouse SEMA4D is typically less than 0.078 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 0.312 ng/ml - 20 ng/ml.

semaphorin-4D/SEMA4D/CD100, ELISA Kit - MBS2603028 from MyBioSource Category ELISA Kit Prices $290.00 Sizes 48 -strip-wells Sensitivity 0.06 ng/ml. Range 20 ng/ml-0.312 ng/ml

Mouse Semaphorin-4D(SEMA4D) ELISA kit - CSB-EL020990MO from Cusabio Category ELISA Kit Sensitivity 0.078 ng/ml. Range 0.312 ng/ml-20 ng/ml

Mouse Semaphorin-4D ELISA - E03S0300 from BlueGene Biotech Category ELISA Kit Sensitivity 0.1 ng/mL

Mouse CD100(Cluster of Differentiation 100) ELISA Kit - E-EL-M0301 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.19 ng/mL Range 0.31~20 ng/mL

Mouse Semaphorin-4D(SEMA4D) ELISA Kit - EKC37788 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,287.50 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.078 ng/ml Range 0.312 ng/ml-20 ng/ml

Mouse CD100 ELISA Kit - E048647 from Biobool Category ELISA Kit

Mouse Sema4d ELISA Kit - E067246 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of mouse SEMA4D is typically less than 0.078 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the

Mouse SEMA4D/CD100 ELISA Kit - E067286 from Biobool Category ELISA Kit Sensitivity 0.06 ng/ml.

SEMA4D ELISA Kit (Mouse) (OKCD02880) - OKCD02880 from Aviva Systems Biology Category ELISA Kit Prices $535.00 Sizes 50 ng Sensitivity 0.30 ng/mL Range 0.78-50 ng/mL

Mouse Semaphorin-4D (SEMA4D) ELISA Kit - AE20169MO from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity 0.30 ng/mL Range 0.78-50 ng/mL

Semaphorin-4D, ELISA Kit - MBS2883714 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mouse SEMA4D ELISA Kit - orb408968 from Biorbyt Category ELISA Kit Sensitivity 0.078 ng/ml. Range 0.312 ng/ml-20 ng/ml

Mouse Semaphorin-4D (SEMA4D) ELISA kit - EKC41908 from Biomatik Category ELISA Kit Prices $709.00 Sizes 96 tests Sensitivity 0.078 ng/mL Range 0.312 ng/mL-20 ng/mL

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