Gene Symbol | Acpp |
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Entrez Gene | 56318 |
Alt Symbol | 5'-NT, A030005E02Rik, FRAP, Lap, PAP, Ppal |
Species | Mouse |
Gene Type | protein-coding |
Description | acid phosphatase, prostate |
Other Description | 5'-nucleotidase|TMPase|ecto-5'-nucleotidase|fluoride-resistant acid phosphatase|lysosomal acid phosphatase|prostatic acid phosphatase|thiamine monophosphatase |
Swissprots | B8JJZ5 A4QPG2 Q8CE08 Q9QXH7 Q8C682 B8JJZ6 |
Accessions | EDL21089 EDL21090 EDL21091 Q8CE08 AA589479 AF210243 AAF23171 AK020693 AK029273 BAC26366 AK076383 BAC36318 AK163330 BAE37304 AK194238 BB760697 BC139826 AAI39827 BI697921 CD770300 NM_019807 NP_062781 NM_207668 NP_997551 |
Function | A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma (By similarity). {ECO:0000250}. |
Subcellular Location | Isoform 1: Secreted {ECO:0000250}. |
Tissue Specificity | Isoform 1 is expressed in salivary gland, thymus and thyroid gland. Isoform 2 is widely expressed in prostate lobes, brain, kidney, liver, lung, muscle, placenta, salivary gland, spleen, thyroid and thymus. Locates to Schwann cells and fibroblasts. Expressed in peptidergic and non- peptidergic nociceptive (pain-sensing) neurons. Preferentially expressed in non-peptidergic doral root ganglia neurons. {ECO:0000269|PubMed:17638863, ECO:0000269|PubMed:18940592, ECO:0000269|PubMed:20084276}. |
Top Pathways | Riboflavin metabolism |
Prostatic Acid Phosphatase Antibody, Mouse, ELISA Kit - E03P0609 from ARP American Research Products
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Prostatic acid phosphatase, Acpp, Mouse, ELISA Kit - E0168m from ARP American Research Products
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Prostatic Acid Phosphatase Antibody, ELISA Kit - MBS724027 from MyBioSource
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Prostatic Acid Phosphatase Antibody, ELISA Kit - MBS007803 from MyBioSource
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Prostatic Acid Phosphatase, PAP, ELISA Kit - MBS701405 from MyBioSource
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Mouse Prostatic Acid Phosphatase,PAP ELISA Kit - CSB-E08280m from Cusabio
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Mouse Prostatic Acid Phosphatase ELISA Kit - abx053622 from Abbexa
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Mouse Prostatic acid phosphatase ELISA Kit - EKE52985 from Biomatik
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Mouse FRAP ELISA Kit - E053194 from Biobool
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Mouse Acpp ELISA Kit - E064941 from Biobool
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ACPP ELISA Kit (Mouse) (OKEH04144) - OKEH04144 from Aviva Systems Biology
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Mouse PAP ELISA Kit - orb409307 from Biorbyt
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