CCDC109B

Gene Symbol CCDC109B
Entrez Gene 55013
Alt Symbol MCUb
Species Human
Gene Type protein-coding
Description coiled-coil domain containing 109B
Other Description calcium uniporter regulatory subunit MCUb, mitochondrial|coiled-coil domain-containing protein 109B|mitochondrial calcium uniporter regulatory subunit MCUb
Swissprots Q9NWR8 Q6IAC1 A8K4Y3
Accessions EAX06242 EAX06243 Q9NWR8 AK000654 BAA91309 AK095936 AK291098 BAF83787 AK311030 AL832311 BC002633 AAH02633 BM830891 CN427680 CR457234 CAG33515 HQ447337 ADQ31823 XM_006714246 XP_006714309 NM_017918 NP_060388
Function Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways. {ECO:0000250|UniProtKB:Q810S1}.
Subcellular Location Mitochondrion inner membrane {ECO:0000269|PubMed:24231807}; Multi-pass membrane protein {ECO:0000269|PubMed:24231807}.

Coiled-coil domain-containing protein 109B (CCDC109B), Human, ELISA Kit - E01C1013 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t
Sensitivity 1.0pg/ml
Range 50-1000pg/ml

Human CCDC109B ELISA Kit - E009955 from Biobool

Category ELISA Kit

Human MCUB ELISA Kit - E089363 from Biobool

Category ELISA Kit
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