CCDC109B

Gene Symbol CCDC109B
Entrez Gene 55013
Alt Symbol MCUb
Species Human
Gene Type protein-coding
Description coiled-coil domain containing 109B
Other Description calcium uniporter regulatory subunit MCUb, mitochondrial|coiled-coil domain-containing protein 109B|mitochondrial calcium uniporter regulatory subunit MCUb
Swissprots Q9NWR8 Q6IAC1 A8K4Y3
Accessions EAX06242 EAX06243 Q9NWR8 AK000654 BAA91309 AK095936 AK291098 BAF83787 AK311030 AL832311 BC002633 AAH02633 BM830891 CN427680 CR457234 CAG33515 HQ447337 ADQ31823 XM_006714246 XP_006714309 NM_017918 NP_060388
Function Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways. {ECO:0000250|UniProtKB:Q810S1}.
Subcellular Location Mitochondrion inner membrane {ECO:0000269|PubMed:24231807}; Multi-pass membrane protein {ECO:0000269|PubMed:24231807}.

Human CCDC109B Gene cDNA Clone - orb142187 from Biorbyt

Prices $264.00
Sizes 10 μg
Species Human

Human-CCDC109B-cDNA-Clone - DC01033 from Abgent, a WuXi AppTec company

Prices $334.80
Sizes 10 µg
Species Human
Accession BC002633

CCDC109B - MBS1277986 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC002633

Human CCDC109B ORF clone (NM_017918.4) - CDCR042278 from Creative biogene

Species Human

Human CCDC109B ORF Clone (BC002633) - CDCS418262 from Creative biogene

Species Human
Accession Q9NWR8

Human CCDC109B ORF clone (BC002633) - CDCB158856 from Creative biogene

Species Human

Human CCDC109B cDNA Clone(NM_017918.4) - CDFG001184 from Creative biogene

Species Human
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