Gene Symbol | Mag |
---|---|
Entrez Gene | 17136 |
Alt Symbol | Gma, siglec-4a |
Species | Mouse |
Gene Type | protein-coding |
Description | myelin-associated glycoprotein |
Other Description | - |
Swissprots | P16880 P20917 |
Accessions | AAA91743 EDL23978 P20917 AK003029 BAB22519 AK045564 BC101944 AAI01945 BC103521 AAI03522 BC103522 AAI03523 BC103523 AAI03524 M31811 AAA39487 X07849 CAA30696 XM_006539590 XP_006539653 XM_006539591 XP_006539654 XM_011250438 XP_011248740 XM_011250439 XP_011248741 XM_011250440 XP_011248742 XM_011250441 XP_011248743 NM_010758 NP_034888 |
Function | Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha-2,3- linked sialic acid. Isoform L-MAG is critical for the formation of myelin in the CNS, whereas isoform S-MAG is sufficient to maintain the integrity of myelin in PNS. {ECO:0000269|PubMed:10625334}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed by myelinating glial cells in the central and peripheral nervous system. Detected in oligodendrocyte processes before formation of compact myelin. Restricted to the periaxonal space after myelination. Isoform S-MAG is the predominant isoform in CNS and PNS of the adult. {ECO:0000269|PubMed:10625334, ECO:0000269|PubMed:1716323}. |
Top Pathways | Cell adhesion molecules (CAMs) |
Recombinant Mouse Myelin-associated glycoprotein(Mag) - CSB-YP013322MO CSB-EP013322MO CSB-BP013322MO CSB-MP013322MO from Cusabio
|
||||||||||
Mouse MAG / GMA / Siglec-4 Protein (His Tag) - 51398-M08H-20 from Sino Biological
|
||||||||||
Mouse MAG / GMA / Siglec-4 Protein (ECD, Fc Tag) - 51398-M02H-20 from Sino Biological
|
||||||||||
Mouse MAG / GMA / Siglec-4 Protein (His Tag) - PKSM040311 from Elabscience
|
||||||||||
Mouse MAG / GMA / Siglec-4 Protein (ECD, Fc Tag) - PKSM040314 from Elabscience
|
||||||||||
Recombinant Mouse MAG Protein - MAG-9442M from Creative Biomart
|
||||||||||
Mouse MAG protein - orb363527 from Biorbyt
|
||||||||||
Mouse MAG protein - orb363544 from Biorbyt
|
||||||||||
Mouse MAG / GMA / Siglec-4 Protein (ECD, Fc Tag) - 51398-M02H from ABclonal
|
||||||||||
Mouse MAG / GMA / Siglec-4 Protein (His Tag) - 51398-M08H from ABclonal
|
||||||||||
MAG / GMA / Siglec-4, Recombinant Protein - MBS2546617 from MyBioSource
|
||||||||||
MAG / GMA / Siglec-4, Recombinant Protein - MBS2546619 from MyBioSource
|
||||||||||
Myelin-associated glycoprotein, Recombinant Protein - MBS7043060 from MyBioSource
|
||||||||||
Myelin-associated glycoprotein (Mag), Recombinant Protein - MBS966173 from MyBioSource
|
||||||||||
Recombinant Mouse Myelin-associated Glycoprotein,Siglec-4a (C-6His) - AP76477 from Signalway Antibody
|
||||||||||
Mouse Siglec-4a protein - orb419978 from Biorbyt
|
||||||||||
Recombinant Mouse Mag Protein, His-tagged - Mag-475M from Creative Biomart
|
||||||||||
Recombinant Mouse Mag Protein, Fc-tagged - Mag-476M from Creative Biomart
|
||||||||||