Gene Symbol | Gja1 |
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Entrez Gene | 24392 |
Alt Symbol | Cx43 |
Species | Rat |
Gene Type | protein-coding |
Description | gap junction protein, alpha 1 |
Other Description | connexin 43|connexin-43|gap junction 43 kDa heart protein|gap junction alpha-1 protein|gap junction membrane channel protein alpha 1 |
Swissprots | P08050 Q53ZE1 |
Accessions | EDL92907 EDL92908 EDL92909 EDL92910 P08050 AY324140 AAP88589 AY555736 AAS68153 AY555737 AAS68154 AY555738 AAS68155 AY555739 AAS68156 AY555740 AAS68157 BC081842 AAH81842 XM_006256503 XP_006256565 NM_012567 NP_036699 |
Function | Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:18636092}; Multi-pass membrane protein {ECO:0000269|PubMed:18636092}. Cell junction, gap junction {ECO:0000269|PubMed:18636092}. |
Top Pathways | Gap junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
Rat Connexin 43 Protein - abx066105 from Abbexa
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Connexin 43 (CX43), Rat - 20-6517 from ARP American Research Products
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Recombinant Connexin 43 (CX43) - RPA277Ra01 from Cloud-clone
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Connexin 43 (CX43) - RPU140994 from Biomatik
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Recombinant Rat GJA1 Protein - GJA1-2545R from Creative Biomart
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Gap junction alpha-1 protein (Gja1), Recombinant Protein - MBS967257 from MyBioSource
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Gap junction alpha-1 protein (Gja1), Recombinant Protein - MBS7015674 from MyBioSource
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Recombinant Connexin 43 (CX43) - RPU40994 from Biomatik
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GJA1 Recombinant Protein (OPCD02579) - OPCD02579 from Aviva Systems Biology
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Connexin 43 (CX43), Recombinant Protein - MBS2011823 from MyBioSource
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