Gja1

Gene Symbol Gja1
Entrez Gene 24392
Alt Symbol Cx43
Species Rat
Gene Type protein-coding
Description gap junction protein, alpha 1
Other Description connexin 43|connexin-43|gap junction 43 kDa heart protein|gap junction alpha-1 protein|gap junction membrane channel protein alpha 1
Swissprots P08050 Q53ZE1
Accessions EDL92907 EDL92908 EDL92909 EDL92910 P08050 AY324140 AAP88589 AY555736 AAS68153 AY555737 AAS68154 AY555738 AAS68155 AY555739 AAS68156 AY555740 AAS68157 BC081842 AAH81842 XM_006256503 XP_006256565 NM_012567 NP_036699
Function Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:18636092}; Multi-pass membrane protein {ECO:0000269|PubMed:18636092}. Cell junction, gap junction {ECO:0000269|PubMed:18636092}.
Top Pathways Gap junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC)

connexin 43 siRNA (r) - sc-60008 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Rat

connexin 43 shRNA Plasmid (r) - sc-60008-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Rat

CompoZr® Knockout ZFN Kit - CKOZFN54442 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND54442 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

GJA1 siRNA (Rat) - CRR0118 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Rat

GJA1 - MBS8219375 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Rat

shRNA set against Rat GJA1 (NM_012567.2) - SHH301290 from Creative biogene

Category siRNA
Species Reactivities Rat

shRNA set against Rat Gja1(NM_012567.2) - SHH085449 from Creative biogene

Category siRNA
Species Reactivities Rat

GJA1 shRNA Plasmid (Rat) - CHR0118 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Rat

GJA1 miRNA 3'UTR clone - MiUTR1R-02116 from Creative biogene

Species Reactivities Rat
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