Gene Symbol | Slc22a3 |
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Entrez Gene | 20519 |
Alt Symbol | EMT, Oct3, Orct3, Slca22a3 |
Species | Mouse |
Gene Type | protein-coding |
Description | solute carrier family 22 (organic cation transporter), member 3 |
Other Description | organic cation transporter 3|solute carrier family 22 member 3|solute carrier family 22, member 3 |
Swissprots | Q9R209 Q9WTW5 |
Accessions | AAD20238 AAM22155 CAC36405 EDL02059 Q9WTW5 AF078750 AAD20978 AF082566 AAD53007 AK143988 BAE25648 BC137661 AAI37662 BC137662 AAI37663 NM_011395 NP_035525 |
Function | Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain. {ECO:0000269|PubMed:10966924, ECO:0000305}. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Highly expressed in placenta and in kidney cortex, but not in medulla. Low levels found in brain. In the kidney, expressed specifically in the proximal and distal convoluted tubules and within Bowman capsule, but not in the glomerulus. {ECO:0000269|PubMed:10966924, ECO:0000269|PubMed:9933568, ECO:0000305}. |
Top Pathways | Choline metabolism in cancer |
SLC22A3 Antibody - NBP1-80529 from Novus Biologicals
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Slc22a3 antibody - middle region (ARP44027_P050) - ARP44027_P050 from Aviva Systems Biology
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OCT3 antibody - 70R-30698 from Fitzgerald
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SLC22A3 / OCT3 (Center) antibody - AP46026PU-N from Acris Antibodies
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SLC22A3 / OCT3 antibody - PAB8479 from Acris Antibodies
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Anti-SLC22A3 antibody - STJ72697 from St John's Laboratory Ltd
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Slc22a3 Antibody - GWB-MP693I from Genway Biotech
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Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) - PAH774Mu01 from Cloud-clone
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Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) - PAH774Mu02 from Cloud-clone
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Slc22a3-antibody-middle-region-AI12364 - AI12364 from Abgent, a WuXi AppTec company
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OTF3 antibody - 70R-50234 from Fitzgerald
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POU5F1 / OCT4 - BT-MB0046 from Nordic BioSite
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Anti-Human/Mouse OCT3/4 PE - 78011-60 from BioGems
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Slc22a3 antibody - middle region : Biotin (ARP44027_P050-Biotin) - ARP44027_P050-Biotin from Aviva Systems Biology
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Slc22a3 antibody - middle region : FITC (ARP44027_P050-FITC) - ARP44027_P050-FITC from Aviva Systems Biology
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Slc22a3 antibody - middle region : HRP (ARP44027_P050-HRP) - ARP44027_P050-HRP from Aviva Systems Biology
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