AP3S1

Gene Symbol AP3S1
Entrez Gene 1176
Alt Symbol CLAPS3, Sigma3A
Species Human
Gene Type protein-coding
Description adaptor-related protein complex 3, sigma 1 subunit
Other Description AP-3 complex sigma-3A subunit|AP-3 complex subunit sigma-1|AP-3 complex subunit sigma-3A|adapter-related protein complex 3 sigma-1 subunit|adapter-related protein complex 3 subunit sigma-1|adaptor-related protein complex 3 subunit sigma-1|clathrin-associated/assembly/adapter protein, small 3|clathrin-associated/assembly/adaptor protein, small 3 (22kD)|sigma-3A-adaptin|sigma-adaptin 3a|sigma3A-adaptin
Swissprots Q53XL4 O00676 O00721 Q6ICQ2 O00727 O00647 Q92572
Accessions EAW48952 EAW48953 Q92572 AK124911 AK126876 AK311843 BAG34785 BC000804 AAH00804 BC012614 BI600357 BT009833 AAP88835 BX647735 CR450341 CAG29337 D63643 BAA09798 DQ891198 ABM82124 DQ894381 ABM85307 U91932 AAD03779 X99458 CAA67823 XM_011543135 XP_011541437 XM_011543136 XP_011541438 XM_011543137 XP_011541439 XM_011543138 XP_011541440 NM_001002924 NM_001284 NP_001275
Function Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
Subcellular Location Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Tissue Specificity Present in all adult tissues examined. {ECO:0000269|PubMed:8697810, ECO:0000269|PubMed:9118953, ECO:0000269|PubMed:9151686}.
Top Pathways Lysosome

Anti-AP3S1 antibody - ab113099 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of AP3S1 in Human kidney tissue with ab113099 at 20 ug/mL.

Anti-AP3S1 antibody - ab107071 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-AP3S1 antibody (ab107071) at 1/100 dilution + A2058 cell line lysates at 35 µg

Anti-AP3S1 antibody - ab128588 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-AP3S1 antibody (ab128588) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : A549 cell lysate

Anti-AP3S1 antibody - ab105510 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-AP3S1 antibody (ab105510) at 1 µg/ml + Jurkat cell lysate at 10 µg

Anti-AP3S1 antibody - ab167339 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-AP3S1 antibody (ab167339) at 1 µg/mlLane 1 : AP3S1 transfected 293T cell lysateLane 2 : non transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG HRP at 1/2500 dilution

Anti-AP3S1 Antibody (aa1-30, AP) - LS-C251473 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AP3S1 Antibody (aa1-30, APC) - LS-C251474 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AP3S1 Antibody (aa1-30, FITC) - LS-C251476 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AP3S1 Antibody (aa1-30, Biotin) - LS-C251475 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AP3S1 Antibody (N-Terminus) - LS-C81680 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Jurkat cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-AP3S1 Antibody (aa1-30, Azide-free, HRP) - LS-C251477 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AP3S1 Antibody (aa1-30, PE) - LS-C251478 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AP3S1 Antibody - LS-C306277 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-AP3S1 Antibody (aa2-31) - LS-C319518 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AP3S1 Antibody (C-Terminus) - LS-C117126 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
AP3S1 / CLAPS3 antibody LS-C117126 Western blot of 293T cell lysate.

Anti-AP3S1 Antibody (aa1-30) - LS-C156392 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
AP3S1 antibody immunohistochemistry of formalin-fixed and paraffin-embedded human colon carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-AP3S1 Antibody (Internal) - LS-C144389 from LifeSpan Bioscience

Prices $345.00, $1,035.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of AP3S1 in human kidney tissue with AP3S1 antibody at 20 ug/ml.

Anti-AP3S1 Antibody (aa2-193) - LS-C178994 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

AP3S1 Antibody - NBP1-55449 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: AP3S1 Antibody [NBP1-55449] - Jurkat cell lysate, concentration 0.2-1 ug/ml.

AP3S1 Antibody - NBP1-76588 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: AP3S1 Antibody [NBP1-76588] - analysis of AP3S1 in mouse kidney tissue lysate with AP3S1 antibody at (A) 1 and (B) 2 ug/mL.

AP3S1 Antibody - H00001176-B02P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: AP3S1 Antibody [H00001176-B02P] - Analysis of AP3S1 expression in transfected 293T cell line by AP3S1 polyclonal antibody. Lane 1: AP3S1 transfected lysate(21.70 KDa). Lane 2: Non-transfected lysate.

Anti-AP3S1 (241-255) antibody produced in rabbit - A2361 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human AP3S1 was separated on SDS-PAGE, blotted with Anti-AP3S1 (241-255) (<B>Cat. No. A2361</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:250

Anti-AP3S1 antibody produced in rabbit - SAB2100129 from Sigma-Aldrich

Prices $347.50
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-AP3S1: <B>Cat. No.SAB2100129</B>: AP3S1 in Jurkat cell lysate with AP3S1 antibody at 1.0 μg/mL.

Anti-AP3S1 antibody produced in rabbit - SAB3500998 from Sigma-Aldrich

Prices $341.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>AP3S1 Antibody: <B>Cat. No. SAB3500998</B>: Western blot analysis of AP3S1 in Mouse kidney tissue lysate with AP3S1 antibody at (Lane A) 1 and (Lane B) 2 μg/mL .

AP3S1 antibody - N-terminal region (ARP51935_P050) - ARP51935_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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